Enterics fast facts Flashcards

1
Q

V. Cholera

A

cholera toxin–AC

tetracyclines in severe cases

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2
Q

ETEC

A

heat stabile-cGMP
heat labile-cAMP

Flouroquinolones

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3
Q

EPEC

A

LEE T3SS–pedestal formation/ villous blunting

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4
Q

EHEC

A

LEE T3SS-pedestal formation
Shiga toxin- hemmorhagic colitis, HUS

NO ABX

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5
Q

Shigella

A

T3SS-uptake, apotptosis, inflammation

Flouroquinolones

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6
Q

S. dysentaeriae

A

T3SS-uptake, apotptosis, inflammation

Shiga toxin- hemmorhagic colitis, HUS

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7
Q

non-typhoidal salmonella

A

SPI1 T3SS- uptake
SPI2 T3SS- intracellular survival and diarrhea

NO antibiotics
Ciprofloxacin in compromised
hosts

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8
Q

Salmonella Typhi

A

SPI1 T3SS- uptake
SPI2 T3SS- intracellular survival and diarrhea
Capsule
Typhoid toxin

Ciprofloxacin, ceftriaxone

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9
Q

Campylobacter

A

Flagella- motility
cytolethal distending toxin

Erythromycin

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