SR 34 - GI Hormones and Physiology Flashcards
What do these cells produce? Gastric parietal cells
HCl
Intrinsic factor
What do these cells produce? Chief cells
Pepsinogen
What do these cells produce? G cells
Gastrin
Found in the antrum
What do these cells produce? Mucous neck cells
Bicarbonate mucus
Name the receptors on the parietal cell that stimulates hCl release
Histamine
Acetylcholine
Gastrin
Where is most of hte bile acids absorbed?
Terminal ileum
Where is intrinsic factor + B12 absorbed?
Terminal ileum
How may times is the entire bile acid pool circulated during a typical meal?
Twice
What are timulators of gallbladder emptying?
CCK
Vagal inuput
What are the inhibitors of gallbladder emptying?
Somatostatin
Sympathteitcs (you cannot flee and ingest food at the same time)
VIP
What stimulates the release of CCK?
Fat, protein, amino acids, HCl, antral stretch
What inhibits the release of CCK?
Trypsin
Chymotrypsin
What are CCKs actions?
Empties gallbladder
Opens ampulla of vater
Slows gastric emptying
Stimulates pancreatic acinar cell growth and release of exocrine products
What is the source of CCK?
Duodenal mucosal cells
What is the source of secretin?
Duodenal cells (argyrophilic S cells)