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Microbiology 2 > Spirochetes and Chlamydia > Flashcards

Spirochetes and Chlamydia Flashcards

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0
Q

Local nontender ulcer (chancre) in the genitals that forms in 2-10 weeks

A

Primary Syphilis

T pallidum

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1
Q

Microphilic bacteria that lacks TCA

A

Treponema pallidum

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2
Q

Condyloma lata, maculopapular rash at palms soles and feet, fever, headache, malaise, anorexia and lymphadenopathy after 1-3 months

A

Secondary syphilis

T pallidum

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3
Q 
Granulomas (gummas)
Neurosyphilis
- tabes dorsalis: argyll robertson pupil or prostitute's pupil
- dementia paralytica
Aortitis from endarteritis
A

Tertiary syphilis

T pallidum

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4
Q

Condyloma acuminata

Condyloma lata

A

HPV

T pallidum

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5
Q

Aortitis from endarteritis

Aortitis in the coronary artery

A

T pallidum

Kawasaki

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6
Q 
Snuffles/saddle nose
Mulberry molars
Hutchinson triad: hutchinson teeth, deafness, keratitis
Saber shins
Rhagades (whitish lesions on the mouth)
Positive Higoumenaki's sign (unilateral enlargement to detachment of sternoclavicular portion of clavicle)
Clutton's joints (synovitis)
Pulmonary hemorrhage
A

Congenital syphilis

T pallidum

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7
Q

Diagnostic test for primary syphilis

A

Dark field microscopy

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8
Q

Diagnostic test for secondary and tertiary syphilis

A

RPR/VDRL for screening

FTA-ABS for confirmation

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9
Q

Gummas

A

Tertiary syphilis

T pallidum

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10
Q

False positive results for VDRL

A

Viruses EBV, hepatitis
Drugs marijuana
Rheumatic fever, rheumatoid arthritis
Lupus, leprosy

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11
Q

Tabes dorsalis

A

Neurosyphilis
Tertiary syphilis
T pallidum

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12
Q

Influenza like symptoms a few hours after receiving penicillin for syphilis

A

Jarisch Herxheimer reaction

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13
Q

Argyll Robertson pupil

Prostitute’s pupil

A

Tabes dorsalis
Neurosyphilis
Tertiary syphilis
T pallidum

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14
Q

Largest medically important bacteria

A

Borrelia burgdoferi

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15
Q

Dementia paralytica

A

Neurosyphilis
Tertiary syphilis
T pallidum

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16
Q

Aniline dyes

Giemsa or Wright stain

A

Borrelia burgdorferi

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17
Q

Mulberry molars

A

Congenital syphilis

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18
Q

From white footed mouse and white tailed deer

Deer ticks - Ixodes scapularis

A

Borrelia burgdoferi

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19
Q

Hutchinson triad

A

Hutchinson teeth
Keratitis
Deafness

Congenital syphilis
T pallidum

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20
Q

Deer ticks - Ixodes scapularis

A

Borrelia burgdorferi

Babesia microti

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21
Q

Saber shins

A

Congenital syphilis

T pallidum

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22
Q

Lyme disease

A

Borrelia burgdorferi

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23
Q

Whitish lesions at the angle of the mouth

A

Rhagades
Congenital syphilis
T pallidum

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24
Q

Erythema migrans

Target lesions

A

Stage 1 Lyme disease

Borrelia burgdorferi

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25
Q

Higoumenaki’s sign

A

Unilateral enlargement to detachment of the sternoclavicular portion of the clavicle
Congenital syphilis
T pallidum

26
Q

Myocarditis (AV block), Meningitis, Bell’s palsy

A

Stage 2 Lyme disease

Borrelia burgdorferi

27
Q

Autoimmune migratory polyarthritis - onion skin lesions

Acrodermatitis chronica atrophicans - atrophy of the skin and hands

A

Stage 3 Lyme disease

Borrelia burgdorferi

28
Q

Clutton’s joints - synovitis

A

Congenital syphilis

T pallidum

29
Q

Acrodermatitis enteropathica

A

Skin ulcers and poor wound healing secondary to zinc deficiency

30
Q

Pulmonary hemorrhage

A

Weil’s disease
Anthrax
Congenital syphilis

31
Q

DOC for early localized or disseminated Lyme disease

A

Doxycycline

32
Q

DOC for late Lyme disease

A

Penicillin or Ceftriaxone

33
Q

Relapsing fever

Undulating fever

A

Borrelia recurrentis

Brucella abortis

34
Q

Diagnostic of choice for Borrelia recurrentis

A

Microscopy

35
Q

Drug of choice for Borrelia recurrentis

A

Tetracycline or Erythromycin

36
Q

Vector for Borrelia recurrentis

A

Pediculus humanus

37
Q

Shepherd’s crook

A

Hook at one or both pointed ends

Leptospira interrogans

38
Q

EMJH or Fletcher’s medium

A

Leptospira interrogans

39
Q

Organisms found in _ during early Leptospirosis and _ during late Leptospirosis

A

Blood and CSF

Urine

40
Q

Gold standard for diagnostics of Leptospirosis

A

LeptoMAT

41
Q

Calf tenderness

Conjunctival suffusion

A

Acute leptospiremic phase

L interrogans

42
Q

Aseptic meningitis that coincides with appearance of antibody titers
Hepatic necrosis
Glomerulonephritis

A

Immune leptospiruric phase

43
Q

Snow flake lesions in CXR

A

Immune leptospiruric phase

44
Q

Triad of Weil Syndrome

A

Jaundice
Bleeding
Uremia

45
Q

Orange cast skin

A

Weil Syndrome

46
Q

DOC for Leptospirosis

A

Penicillin G

47
Q

Cell wall lacks muramic acid

A

Chlamydia trachomatis

48
Q

Cycloheximide culture

A

Chlamydia trachomatis

49
Q

Halberstadter-Prowazek inclusions in Giemsa

A

Round to oval cytoplasmic inclusion bodies near the nuclei of connunctival epithelial cells in trachoma
Chlamydia trachomatis

50
Q

Most common STD

A

C trachomatis D-K
Neonatal conjunctivitis and pneumonia
Reiter’s syndrome

51
Q

Two forms of Chlamydia

A

Elementary body - Enactive, Extracellular, Endocytosis

Reticulate body - active, intracellular, seen microscopically

52
Q

Trachoma Types
A
B
C

A

Africa
Blindness
Chronic infection

53
Q

Papule or vesicle which ulcerates and leads to suppurative inguinal lymphadenopathy
Positive Frei test

A

Buboes in Lymphogranuloma Venereum

C trachomatis L1-L3

54
Q

Buboes

A

Yersinia

Chlamydia

55
Q

Sudden onset pneumonia with malaise, fever, anorexia, sore throat, photophobia, and severe HA after bird exposure

A

Bird fancier’s disease
Psittacosis
C psittaci

56
Q

DOC for Chlamydia

STD

A

Azithromycin

57
Q

DOC for Chlamydia

Conjunctivitis

A

Erythromycin

58
Q

DOC for Chlamydia

LGV

A

Doxycyxline

59
Q

DOC for Chlamydia

Psittacosis

A

Azithromycin

60
Q

Associated with atherosclerosis

A

C pneumoniae

61
Q

Only disease diagnosed by demonstration of spirochetes in peripheral blood smear

A

Relapsing fever

62
Q

Treponemal test

A

VDRL

Microbiology 2 (13 decks)

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