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Microbiology 2 > Gram Negative Rods - GIT And GUT > Flashcards

Gram Negative Rods - GIT And GUT Flashcards

0
Q

Lactose fermenters

A

MacConKEE
Citrobacter - slow

fast
Klebsiella
E coli
Enterobacter

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1
Q

GN rods
Lactose fermenting on EMB or Mac Conkey’s agar
Metallic green sheen on EMB
Acid slant and acid butt with gas on TSI but not H2S

A

E coli

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2
Q

GN rods

Typing by O and H antigen

A

E coli

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3
Q

Virulence factors of E coli

A

Pili
K capsule
H flagellum
O endotoxin
HST and HLT exotoxins cause watery diarrhea
Verotoxin (shiga like) causes bloody diarrhea

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4
Q

Most common cause of community acquired UTI

A

E coli

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5
Q

Neonatal meningitis

A

BEL
B group streptococci
E coli
Listeria

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6
Q

What kind of E coli would cause the following symptoms?

Watery diarrhea

A

Enterotoxigenic E coli
Montezuma’s revenge
Traveller’s diarrhea
Delhi belly

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7
Q

What kind of E coli would cause the following symptoms?

Watery diarrhea of long duration in Pediatric population of developing countries (Phil)

A

EnteroPathogenic E coli

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8
Q

What kind of E coli would cause the following symptoms?
Bloody diarrhea
Hemorrhagic colitis
Hemorrhagic uremic syndrome (microangiopathic hemolytic anemia)

A

Enterohemorrhagic E coli

0157:H7

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9
Q

What kind of E coli would cause the following symptoms?

Bloody diarrhea

A

Enteroinvasive E coli

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10
Q

What kind of E coli would cause the following symptoms?

Persistent watery diarrhea in patients with AIDS

A

EnteroAdherent E coli

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11
Q

DOC for UTI by E coli

A

Ampicillin or Sulfonamides

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12
Q

DOC for meningitis by E coli

A

3 gen cephalosporins

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13
Q

GN rods
Lactose fermenting on EMB and Mac Conkey’s agar
Urease positive

A

Klebsiella pneumoniae

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14
Q

GN rods

Large polysaccharide capsule causing MUCOID CLEARING

A

Klebsiella

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15
Q

GN rods

ESBL activity in drug resistant chains

A

Klebsiella

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16
Q

Thick bloody or currant jelly sputum
Nosocomial
Most common in alcoholics

A

Necrotizing pneumonia

Klebsiella

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17
Q

DOC for Klebsiella

A

Cephalosporins +/- aminoglycosides

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18
Q

GN rods
Comma shaped
TCBS agar
Oxidase positive

A

Vibrio

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19
Q

Shooting star motility

A

Vibrio

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20
Q

Vibrio in
Human colon
Saltwater

A

V cholerae

V parahaemolyticus and V vulnificus

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21
Q

Virulence factors of Vibrio

A

Enterotoxin choleragen

Mucinase for attachment

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22
Q

Pandemics caused by this Vibrio strain

A

Vibrio cholerae 01 biotype El Tor

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23
Q

ADP ribosylation
Activates Gs
Activates Gi

A

Choleragen of Vibrio

Pertussis toxin

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24
Rice water stools
Cholera | V cholera
25
Explosive onset of watery diarrhea and nausea, vomiting, abdominal cramps, HA and low grade fever Self limited
Gastroenteritis | V parahaemolyticus and V vulnificus
26
Wound infections after exposure to contaminated water
V parahaemolyticus and V vulnificus
27
DOC for V cholera
Tetracycline or azithromycin
28
DOC for V parahaemolyticus and V vulnificus
Minocycline + fluoroquinolone or cefotaxime
29
``` GN rods Comma shaped Oxidase positive Catalase positive Growth on 42C on Skirrow's agar ```
Campylobacter jejuni
30
Most common cause of bacterial gastroenteritis | No invasion of colonic mucosa
C jejuni
31
Watery foul smelling diarrhea followed by bloody stools accompanied by fever and severe abdominal pain UNDERCOOKED CHICKEN
C jejuni
32
Guillain Barre syndrome | Reiter's syndrome
C jejuni
33
GN rods Comma shaped Urease positive
Helicobacter pylori
34
Peptic Ulcer Disease Gastric carcinoma MALT Lymphomas
H pylori
35
Regimen for anti - H pylori | Quadruple therapy
Omeprazole Bismuth Metronidazole Terracycline
36
Regimen for anti - H pylori | Triple therapy
Bismuth Metronidazole Tetracycline Ranitidine Metronidazole Tetracycline Omeprazole Metronidazole Clarithromycin
37
``` GN rods Non lactose fermenting XLD medium H2S producer Motile ```
Salmonella
38
Habitat in Human colon Human and animal colon
S typhi | S paratyphi
39
Positive Widal's test
Salmonella
40
Salmonella from Poultry and egg Iced candy
S enteritidis and S typhimurium causing enterocolitis | S typhi causing typhoid fever
41
VI capsular antigen
S typhi
42
Multiply in Peyer's patches and spread in RES | Gallbladder invasion causes chronic carrier state
Typhoid fever | S typhi
43
DOC for chronic carrier state of typhoid fever
Ampicillin
44
Bacteremia with osteomyelitis, pneumonia and meningitis in patients with sickle cell anemia or cancer
S choleraesuis
45
``` Typhoid fever Culture source Wk 1 Wk 2 Wk 3 Wk 4 Post ```
``` Blood Urine Stool Bone marrow Bile, stool, bone marrow ```
46
``` Typhoid fever Symptomatology Wk 1 Wk 2 Wk 3 Wk 4 Post ```
Stepwise fever and relative bradycardia Rose spots, abdominal pain and hepatosplenomegaly Bleeding, ileitis and pneumonia (complications) Recovery or death Chronic carrier state
47
Typhoid psychosis
Salmonella cerebritis
48
DOC for Salmonella
Ceftriaxone | Phil: amoxicillin, chloramphenicol, cotrimoxazole
49
``` GN rods Non lactose fermenting XLD medium Non lactose fermenters Non motile ```
Shigella
50
Transmission through Food Fingers Feces and Flies
Shigella
51
Most common cause of bacillary dysentery
Group D Shigella sonnei Duval's bacillus
52
Most severe form of bacillary dysentery
Group A Shigella dysenteriae Type 1 Shiga bacillus Shiga toxin
53
Most common cause of epidemic dysentery
Group A Shigella dysenteriae Type 1 Shiga bacillus Shiga toxin
54
Schmitz bacillus
Group A Shigella dysenteriae Type 2
55
Hiss and Russel's bacillus
Group B | Shigella flexneri
56
Newcastle Manchester bacillus
Group C | Shigella boydii
57
DOC for Shigella
Ciprofloxacin
58
``` GN rods Non lactose fermenting H2S producer Urease positive Oxidase negative ```
Proteus mirabilis
59
Swarming motility
Proteus
60
Struvite stones composed of magnesium ammonium phosphate | Staghorn calculi
Proteus
61
DOC for Proteus
TMP SMX or penicillin
62
GN rods Non lactose fermenting Cetirimide agar Oxidase positive
Pseudomonas aeruginosa
63
Pyocyanin
Pseudomonas
64
Sweet grapelike odor
Pseudomonas
65
Hospital respirators and humidifiers | Medical liquids meant to be sterile
Pseudomonas
66
Endotoxin Exotoxin with type III secretion system Elastase and protease
Pseudomonas
67
Verdoglobin
Pseudomonas
68
Burn wound infections | Skin graft loss
Pseudomonas aeruginosa
69
Green nail syndrome
Pseudomonas aeruginosa
70
Hot tub folliculitis
Pseudomonas
71
Puncture wound and pubic osteomyelitis
Pseudomonas
72
Most common cause of otitis externa
Pseudomonas
73
Most common cause of malignant otitis externa in DM
Pseudomonas
74
Most common cause of CSOM
Pseudomonas
75
VAP and HR CAP in patients with brochiectasis and cystic fibrosis
Pseudomonas
76
Typhlitis or necrotizing colitis Shanghai fever Peritonitis in patients undergoing dialysis
Pseudomonas
77
Ecthyma gangrenosum | Febrile neutropenia
Pseudomonas aeruginosa
78
3rd most common cause of nosocomial UTI
Pseudomonas
79
Predominant anaerobe of human colon which spreads to blood or peritoneum during bowel trauma, perforation or surgery Abdominal abscess
Bacteroides fragilis | GN rods
80
When typhoid fever symptoms first become apparent, Salmonella typhi is the most frequently isolated from
Blood
81
Most infectious of the GN rods producing AGE
Shigella dysenteriae type 1

Microbiology 2 (13 decks)

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