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Microbiology 2 > Gram Negative Rods - GIT And GUT > Flashcards

Gram Negative Rods - GIT And GUT Flashcards

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0
Q

Lactose fermenters

A

MacConKEE
Citrobacter - slow

fast
Klebsiella
E coli
Enterobacter

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1
Q

GN rods
Lactose fermenting on EMB or Mac Conkey’s agar
Metallic green sheen on EMB
Acid slant and acid butt with gas on TSI but not H2S

A

E coli

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2
Q

GN rods

Typing by O and H antigen

A

E coli

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3
Q

Virulence factors of E coli

A

Pili
K capsule
H flagellum
O endotoxin
HST and HLT exotoxins cause watery diarrhea
Verotoxin (shiga like) causes bloody diarrhea

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4
Q

Most common cause of community acquired UTI

A

E coli

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5
Q

Neonatal meningitis

A

BEL
B group streptococci
E coli
Listeria

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6
Q

What kind of E coli would cause the following symptoms?

Watery diarrhea

A

Enterotoxigenic E coli
Montezuma’s revenge
Traveller’s diarrhea
Delhi belly

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7
Q

What kind of E coli would cause the following symptoms?

Watery diarrhea of long duration in Pediatric population of developing countries (Phil)

A

EnteroPathogenic E coli

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8
Q

What kind of E coli would cause the following symptoms?
Bloody diarrhea
Hemorrhagic colitis
Hemorrhagic uremic syndrome (microangiopathic hemolytic anemia)

A

Enterohemorrhagic E coli

0157:H7

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9
Q

What kind of E coli would cause the following symptoms?

Bloody diarrhea

A

Enteroinvasive E coli

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10
Q

What kind of E coli would cause the following symptoms?

Persistent watery diarrhea in patients with AIDS

A

EnteroAdherent E coli

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11
Q

DOC for UTI by E coli

A

Ampicillin or Sulfonamides

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12
Q

DOC for meningitis by E coli

A

3 gen cephalosporins

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13
Q

GN rods
Lactose fermenting on EMB and Mac Conkey’s agar
Urease positive

A

Klebsiella pneumoniae

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14
Q

GN rods

Large polysaccharide capsule causing MUCOID CLEARING

A

Klebsiella

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15
Q

GN rods

ESBL activity in drug resistant chains

A

Klebsiella

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16
Q

Thick bloody or currant jelly sputum
Nosocomial
Most common in alcoholics

A

Necrotizing pneumonia

Klebsiella

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17
Q

DOC for Klebsiella

A

Cephalosporins +/- aminoglycosides

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18
Q

GN rods
Comma shaped
TCBS agar
Oxidase positive

A

Vibrio

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19
Q

Shooting star motility

A

Vibrio

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20
Q

Vibrio in
Human colon
Saltwater

A

V cholerae

V parahaemolyticus and V vulnificus

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21
Q

Virulence factors of Vibrio

A

Enterotoxin choleragen

Mucinase for attachment

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22
Q

Pandemics caused by this Vibrio strain

A

Vibrio cholerae 01 biotype El Tor

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23
Q

ADP ribosylation
Activates Gs
Activates Gi

A

Choleragen of Vibrio

Pertussis toxin

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24
Q

Rice water stools

A

Cholera

V cholera

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25
Q

Explosive onset of watery diarrhea and nausea, vomiting, abdominal cramps, HA and low grade fever
Self limited

A

Gastroenteritis

V parahaemolyticus and V vulnificus

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26
Q

Wound infections after exposure to contaminated water

A

V parahaemolyticus and V vulnificus

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27
Q

DOC for V cholera

A

Tetracycline or azithromycin

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28
Q

DOC for V parahaemolyticus and V vulnificus

A

Minocycline + fluoroquinolone or cefotaxime

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29
Q 
GN rods
Comma shaped
Oxidase positive
Catalase positive
Growth on 42C on Skirrow's agar
A

Campylobacter jejuni

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30
Q

Most common cause of bacterial gastroenteritis

No invasion of colonic mucosa

A

C jejuni

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31
Q

Watery foul smelling diarrhea followed by bloody stools accompanied by fever and severe abdominal pain
UNDERCOOKED CHICKEN

A

C jejuni

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32
Q

Guillain Barre syndrome

Reiter’s syndrome

A

C jejuni

33
Q

GN rods
Comma shaped
Urease positive

A

Helicobacter pylori

34
Q

Peptic Ulcer Disease
Gastric carcinoma
MALT Lymphomas

A

H pylori

35
Q

Regimen for anti - H pylori

Quadruple therapy

A

Omeprazole
Bismuth
Metronidazole
Terracycline

36
Q

Regimen for anti - H pylori

Triple therapy

A

Bismuth Metronidazole Tetracycline
Ranitidine Metronidazole Tetracycline
Omeprazole Metronidazole Clarithromycin

37
Q 
GN rods
Non lactose fermenting
XLD medium
H2S producer
Motile
A

Salmonella

38
Q

Habitat in
Human colon
Human and animal colon

A

S typhi

S paratyphi

39
Q

Positive Widal’s test

A

Salmonella

40
Q

Salmonella from
Poultry and egg
Iced candy

A

S enteritidis and S typhimurium causing enterocolitis

S typhi causing typhoid fever

41
Q

VI capsular antigen

A

S typhi

42
Q

Multiply in Peyer’s patches and spread in RES

Gallbladder invasion causes chronic carrier state

A

Typhoid fever

S typhi

43
Q

DOC for chronic carrier state of typhoid fever

A

Ampicillin

44
Q

Bacteremia with osteomyelitis, pneumonia and meningitis in patients with sickle cell anemia or cancer

A

S choleraesuis

45
Q 
Typhoid fever
Culture source
Wk 1
Wk 2
Wk 3
Wk 4
Post
A 
Blood
Urine
Stool
Bone marrow
Bile, stool, bone marrow
46
Q 
Typhoid fever
Symptomatology
Wk 1
Wk 2
Wk 3
Wk 4
Post
A

Stepwise fever and relative bradycardia
Rose spots, abdominal pain and hepatosplenomegaly
Bleeding, ileitis and pneumonia (complications)
Recovery or death
Chronic carrier state

47
Q

Typhoid psychosis

A

Salmonella cerebritis

48
Q

DOC for Salmonella

A

Ceftriaxone

Phil: amoxicillin, chloramphenicol, cotrimoxazole

49
Q 
GN rods
Non lactose fermenting
XLD medium
Non lactose fermenters
Non motile
A

Shigella

50
Q

Transmission through Food Fingers Feces and Flies

A

Shigella

51
Q

Most common cause of bacillary dysentery

A

Group D
Shigella sonnei
Duval’s bacillus

52
Q

Most severe form of bacillary dysentery

A

Group A
Shigella dysenteriae
Type 1 Shiga bacillus
Shiga toxin

53
Q

Most common cause of epidemic dysentery

A

Group A
Shigella dysenteriae
Type 1 Shiga bacillus
Shiga toxin

54
Q

Schmitz bacillus

A

Group A
Shigella dysenteriae
Type 2

55
Q

Hiss and Russel’s bacillus

A

Group B

Shigella flexneri

56
Q

Newcastle Manchester bacillus

A

Group C

Shigella boydii

57
Q

DOC for Shigella

A

Ciprofloxacin

58
Q 
GN rods
Non lactose fermenting
H2S producer
Urease positive
Oxidase negative
A

Proteus mirabilis

59
Q

Swarming motility

A

Proteus

60
Q

Struvite stones composed of magnesium ammonium phosphate

Staghorn calculi

A

Proteus

61
Q

DOC for Proteus

A

TMP SMX or penicillin

62
Q

GN rods
Non lactose fermenting
Cetirimide agar
Oxidase positive

A

Pseudomonas aeruginosa

63
Q

Pyocyanin

A

Pseudomonas

64
Q

Sweet grapelike odor

A

Pseudomonas

65
Q

Hospital respirators and humidifiers

Medical liquids meant to be sterile

A

Pseudomonas

66
Q

Endotoxin
Exotoxin with type III secretion system
Elastase and protease

A

Pseudomonas

67
Q

Verdoglobin

A

Pseudomonas

68
Q

Burn wound infections

Skin graft loss

A

Pseudomonas aeruginosa

69
Q

Green nail syndrome

A

Pseudomonas aeruginosa

70
Q

Hot tub folliculitis

A

Pseudomonas

71
Q

Puncture wound and pubic osteomyelitis

A

Pseudomonas

72
Q

Most common cause of otitis externa

A

Pseudomonas

73
Q

Most common cause of malignant otitis externa in DM

A

Pseudomonas

74
Q

Most common cause of CSOM

A

Pseudomonas

75
Q

VAP and HR CAP in patients with brochiectasis and cystic fibrosis

A

Pseudomonas

76
Q

Typhlitis or necrotizing colitis
Shanghai fever
Peritonitis in patients undergoing dialysis

A

Pseudomonas

77
Q

Ecthyma gangrenosum

Febrile neutropenia

A

Pseudomonas aeruginosa

78
Q

3rd most common cause of nosocomial UTI

A

Pseudomonas

79
Q

Predominant anaerobe of human colon which spreads to blood or peritoneum during bowel trauma, perforation or surgery
Abdominal abscess

A

Bacteroides fragilis

GN rods

80
Q

When typhoid fever symptoms first become apparent, Salmonella typhi is the most frequently isolated from

A

Blood

81
Q

Most infectious of the GN rods producing AGE

A

Shigella dysenteriae type 1

Microbiology 2 (13 decks)

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