Mycology Flashcards

0
Q

Thermal dimorphism in fungi
Room temp
Body temp

A

Mold

Yeast

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1
Q

Major membrane sterol of fungi

A

Ergosterol

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2
Q

Laboratory Diagnosis

Microscopy of _ preparation

A

KOH

Dissolves human cells

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3
Q

Laboratory Diagnosis

_ agar

A

Saboraud’s

Low pH inhibits bacterial growth

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4
Q

Amanita mushrooms

A

Amanitin and phylloidin

Liver necrosis

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5
Q

Aspergillus flavus

A

aflatoxin

Liver cancer

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6
Q

Aspergillus fumigatus

A

Allergic bronchopulmonary aspergillosis (IgE mediated)

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7
Q

Cutaneous mycoses

A

Dermatophytoses
Malassezia furfur
Sporotrix schenkii

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8
Q

Systemic Mycoses

A

Coccidioses immitis
Histoplasma capsulatum
Blastomycoses dermatidis
Paracoccidiodes brasiliensis

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9
Q

Opportunistic Mycoses

A
Candida albicans
Cryptococcus neoformans
Aspergillus fumigatus
Mucormycosis
Pneumocystis jiroveci
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10
Q

Infect only superficial keratinized structures

A

Dermatophytoses

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11
Q

Important dermatophytes

A

Microsporum canis
Trichophyton tonsurans
Epidermophyton floccosum

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12
Q

Inflamed circular border containing papules and vesicles surrounded by clear area of relatively normal skin

A

Dermatophytoses

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13
Q

Hypersensitivity found in an area distant to the infection

A

Ghost reaction

Dermatophytid reaction

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14
Q

10% KOH: septate hyphae

Saboraud’s agar: hyphae and conidia

A

Dermatophytoses

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15
Q

Dermatophytoses

Wood’s lamp

A

Green fluorescence

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16
Q

Treatment for dermatophytoses

A

Local antifungal cream

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17
Q

Tinea versicolor

An-an

A

Malassezia furfur

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18
Q

Malassezia furfur

10% KOH

A

Spaghetti and meatballs

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19
Q

Treatment for Malassezia furfur

A

Miconazole

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20
Q

Dimorphic fungus that lives on vegetation

Transmitted to gardeners particularly rose pruners through THORN PRICK

A

Sporotrichisis
Sporothrix schenkii
Itraconazole or KI

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21
Q

Latin America and Southwestern USA
Mold in soil
Spherule in tissue

A

Coccidioides immitis

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22
Q

Inhalation of ARTHROSPORES
Erythema nodosum or dessert bumps for intact CMI
Granulomata in bones and CNS for defective CMI

A

VALLEY FEVER
Coccidioides immitis
Amphotericin B

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23
Q

Two asexual spore types of Histoplasma capsulatum

A

Tuberculate macroconidia diagnosis

Microconidia transmission

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24
Endemic in Ohio and Mississippi river valleys (eastern North America)
Histoplasma capsulatum | Blastomycoses dermatitis
25
Grows in soil contaminated with bird droppings or STARLINGS bat guano
Histoplasma capsulatum | Amphotericin B
26
TB mimicker
Histoplasma capsulatum | Paragonimus westermani
27
Round yeast with BROAD BASED bud
Blastomycoses dermatitidis
28
Most common cause of chronic fungal pneumonia
Blastomycoses dermatitidis | Itraconazole
29
Thick yeast with multiple buds in wheel configuration
MARINER'S WHEEL | Paracoccidioides brasiliensis
30
Central and South America
Paracoccidioides brasiliensis | Itraconazole
31
Lutz Almeda de Splendor disease
Paracoccidioides lutzir
32
Germ tubes in serum | Chlamydospores in culture
Candida albicans
33
Vulvovaginitis with curdlike discharge
Immunocompetent C albicans Disseminated - amphotericin B
34
Satellite lesions
Immunocompetent C albicans Clotrimazole
35
Whitish yellowish plaque | Pseudomembranous esophagitis
Immunocompromised C albicans Nystatin swish and swallow
36
Chemoprophylaxis for C albicans
Fluconazole
37
Pseudohyphae
C albicans
38
Oval yeast with NARROW BASED bud surrounded by polysaccharide capsule in India ink (NEGATIVE STAINING)
Cryptococcus neoformans
39
C neoformans var neoformans var gatti
Bird droppings | Eucalyptus tree
40
Most common cause of meningitis in HIV patients presenting as chronic HA and benign dizziness
Cryptococcus neoformans
41
Asymptomatic pneumonia
Cryptococcus neoformans
42
DOC for C neoformans
Amphotericin B | Flucytosine
43
Chemoprophylaxis for C neoformans
Fluconazole
44
Septate hyphae that form V SHAPED/DICHOTOMOUS BRANCHES
Aspergillus
45
Aspergilloma
Aspergillus fumigatus | Amphotericin B
46
Asthmatic symptoms with expectoration of brownish bronchial plugs
Allergic bronchopulmonary aspergillosis
47
Mucormycosis
Rhizopus oryzae | Mucor spp
48
Nonseptate hyphae with branches at RIGHT ANGLES
Mucormycosis
49
RHINOORBITALCEREBRAL infection with eschar formation in patients with DKA, burns or leukemia
Mucormycosis
50
Indeterminate organism with major surface glycoprotein that undergoes programmed rearrangements
Pneumocystic jiroveci/carinii
51
Diagnosis of Pneumocystic jiroveci/carinii
BAL washings - toluidine blue - methenamine silver stain
52
Inhalation of CYSTS cause FROTHY EXUDATE that blocks oxygen exchange leading to ARDS
Pneumocystic jiroveci/carinii
53
Bilateral ground glass infiltrates
PCP | Pneumocystic jiroveci/carinii
54
Most common AIDS defining illness
PCP CD4<200 Pneumocystic jiroveci/carinii
55
DOC for PCP
TMP-SMX
56
Spelunker's disease
Histoplasma
57
Diagnostic test for Histoplasma
Culture
58
Wood's lamp Dermatophytoses Malassezia furfur
Green | Orange
59
Asteroid bodies
Sporotrix schenkii
60
10% potassium hydroxide cleared lesion scrapings reveal typical, thick-walled, cigar-colored, sclerotic cells, also known as Medlar bodies, are readily seen.
Chromomycosis
61
Copper pennies on histology
Chromomycosis