Mycology Flashcards
Thermal dimorphism in fungi
Room temp
Body temp
Mold
Yeast
Major membrane sterol of fungi
Ergosterol
Laboratory Diagnosis
Microscopy of _ preparation
KOH
Dissolves human cells
Laboratory Diagnosis
_ agar
Saboraud’s
Low pH inhibits bacterial growth
Amanita mushrooms
Amanitin and phylloidin
Liver necrosis
Aspergillus flavus
aflatoxin
Liver cancer
Aspergillus fumigatus
Allergic bronchopulmonary aspergillosis (IgE mediated)
Cutaneous mycoses
Dermatophytoses
Malassezia furfur
Sporotrix schenkii
Systemic Mycoses
Coccidioses immitis
Histoplasma capsulatum
Blastomycoses dermatidis
Paracoccidiodes brasiliensis
Opportunistic Mycoses
Candida albicans Cryptococcus neoformans Aspergillus fumigatus Mucormycosis Pneumocystis jiroveci
Infect only superficial keratinized structures
Dermatophytoses
Important dermatophytes
Microsporum canis
Trichophyton tonsurans
Epidermophyton floccosum
Inflamed circular border containing papules and vesicles surrounded by clear area of relatively normal skin
Dermatophytoses
Hypersensitivity found in an area distant to the infection
Ghost reaction
Dermatophytid reaction
10% KOH: septate hyphae
Saboraud’s agar: hyphae and conidia
Dermatophytoses
Dermatophytoses
Wood’s lamp
Green fluorescence
Treatment for dermatophytoses
Local antifungal cream
Tinea versicolor
An-an
Malassezia furfur
Malassezia furfur
10% KOH
Spaghetti and meatballs
Treatment for Malassezia furfur
Miconazole
Dimorphic fungus that lives on vegetation
Transmitted to gardeners particularly rose pruners through THORN PRICK
Sporotrichisis
Sporothrix schenkii
Itraconazole or KI
Latin America and Southwestern USA
Mold in soil
Spherule in tissue
Coccidioides immitis
Inhalation of ARTHROSPORES
Erythema nodosum or dessert bumps for intact CMI
Granulomata in bones and CNS for defective CMI
VALLEY FEVER
Coccidioides immitis
Amphotericin B
Two asexual spore types of Histoplasma capsulatum
Tuberculate macroconidia diagnosis
Microconidia transmission