Mycology Flashcards

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0
Q

Thermal dimorphism in fungi
Room temp
Body temp

A

Mold

Yeast

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1
Q

Major membrane sterol of fungi

A

Ergosterol

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2
Q

Laboratory Diagnosis

Microscopy of _ preparation

A

KOH

Dissolves human cells

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3
Q

Laboratory Diagnosis

_ agar

A

Saboraud’s

Low pH inhibits bacterial growth

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4
Q

Amanita mushrooms

A

Amanitin and phylloidin

Liver necrosis

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5
Q

Aspergillus flavus

A

aflatoxin

Liver cancer

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6
Q

Aspergillus fumigatus

A

Allergic bronchopulmonary aspergillosis (IgE mediated)

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7
Q

Cutaneous mycoses

A

Dermatophytoses
Malassezia furfur
Sporotrix schenkii

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8
Q

Systemic Mycoses

A

Coccidioses immitis
Histoplasma capsulatum
Blastomycoses dermatidis
Paracoccidiodes brasiliensis

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9
Q

Opportunistic Mycoses

A
Candida albicans
Cryptococcus neoformans
Aspergillus fumigatus
Mucormycosis
Pneumocystis jiroveci
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10
Q

Infect only superficial keratinized structures

A

Dermatophytoses

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11
Q

Important dermatophytes

A

Microsporum canis
Trichophyton tonsurans
Epidermophyton floccosum

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12
Q

Inflamed circular border containing papules and vesicles surrounded by clear area of relatively normal skin

A

Dermatophytoses

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13
Q

Hypersensitivity found in an area distant to the infection

A

Ghost reaction

Dermatophytid reaction

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14
Q

10% KOH: septate hyphae

Saboraud’s agar: hyphae and conidia

A

Dermatophytoses

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15
Q

Dermatophytoses

Wood’s lamp

A

Green fluorescence

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16
Q

Treatment for dermatophytoses

A

Local antifungal cream

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17
Q

Tinea versicolor

An-an

A

Malassezia furfur

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18
Q

Malassezia furfur

10% KOH

A

Spaghetti and meatballs

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19
Q

Treatment for Malassezia furfur

A

Miconazole

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20
Q

Dimorphic fungus that lives on vegetation

Transmitted to gardeners particularly rose pruners through THORN PRICK

A

Sporotrichisis
Sporothrix schenkii
Itraconazole or KI

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21
Q

Latin America and Southwestern USA
Mold in soil
Spherule in tissue

A

Coccidioides immitis

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22
Q

Inhalation of ARTHROSPORES
Erythema nodosum or dessert bumps for intact CMI
Granulomata in bones and CNS for defective CMI

A

VALLEY FEVER
Coccidioides immitis
Amphotericin B

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23
Q

Two asexual spore types of Histoplasma capsulatum

A

Tuberculate macroconidia diagnosis

Microconidia transmission

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24
Q

Endemic in Ohio and Mississippi river valleys (eastern North America)

A

Histoplasma capsulatum

Blastomycoses dermatitis

25
Q

Grows in soil contaminated with
bird droppings or STARLINGS
bat guano

A

Histoplasma capsulatum

Amphotericin B

26
Q

TB mimicker

A

Histoplasma capsulatum

Paragonimus westermani

27
Q

Round yeast with BROAD BASED bud

A

Blastomycoses dermatitidis

28
Q

Most common cause of chronic fungal pneumonia

A

Blastomycoses dermatitidis

Itraconazole

29
Q

Thick yeast with multiple buds in wheel configuration

A

MARINER’S WHEEL

Paracoccidioides brasiliensis

30
Q

Central and South America

A

Paracoccidioides brasiliensis

Itraconazole

31
Q

Lutz Almeda de Splendor disease

A

Paracoccidioides lutzir

32
Q

Germ tubes in serum

Chlamydospores in culture

A

Candida albicans

33
Q

Vulvovaginitis with curdlike discharge

A

Immunocompetent
C albicans
Disseminated - amphotericin B

34
Q

Satellite lesions

A

Immunocompetent
C albicans
Clotrimazole

35
Q

Whitish yellowish plaque

Pseudomembranous esophagitis

A

Immunocompromised
C albicans
Nystatin swish and swallow

36
Q

Chemoprophylaxis for C albicans

A

Fluconazole

37
Q

Pseudohyphae

A

C albicans

38
Q

Oval yeast with NARROW BASED bud surrounded by polysaccharide capsule in India ink (NEGATIVE STAINING)

A

Cryptococcus neoformans

39
Q

C neoformans
var neoformans
var gatti

A

Bird droppings

Eucalyptus tree

40
Q

Most common cause of meningitis in HIV patients presenting as chronic HA and benign dizziness

A

Cryptococcus neoformans

41
Q

Asymptomatic pneumonia

A

Cryptococcus neoformans

42
Q

DOC for C neoformans

A

Amphotericin B

Flucytosine

43
Q

Chemoprophylaxis for C neoformans

A

Fluconazole

44
Q

Septate hyphae that form V SHAPED/DICHOTOMOUS BRANCHES

A

Aspergillus

45
Q

Aspergilloma

A

Aspergillus fumigatus

Amphotericin B

46
Q

Asthmatic symptoms with expectoration of brownish bronchial plugs

A

Allergic bronchopulmonary aspergillosis

47
Q

Mucormycosis

A

Rhizopus oryzae

Mucor spp

48
Q

Nonseptate hyphae with branches at RIGHT ANGLES

A

Mucormycosis

49
Q

RHINOORBITALCEREBRAL infection with eschar formation in patients with DKA, burns or leukemia

A

Mucormycosis

50
Q

Indeterminate organism with major surface glycoprotein that undergoes programmed rearrangements

A

Pneumocystic jiroveci/carinii

51
Q

Diagnosis of Pneumocystic jiroveci/carinii

A

BAL washings

  • toluidine blue
  • methenamine silver stain
52
Q

Inhalation of CYSTS cause FROTHY EXUDATE that blocks oxygen exchange leading to ARDS

A

Pneumocystic jiroveci/carinii

53
Q

Bilateral ground glass infiltrates

A

PCP

Pneumocystic jiroveci/carinii

54
Q

Most common AIDS defining illness

A

PCP
CD4<200
Pneumocystic jiroveci/carinii

55
Q

DOC for PCP

A

TMP-SMX

56
Q

Spelunker’s disease

A

Histoplasma

57
Q

Diagnostic test for Histoplasma

A

Culture

58
Q

Wood’s lamp
Dermatophytoses
Malassezia furfur

A

Green

Orange

59
Q

Asteroid bodies

A

Sporotrix schenkii

60
Q

10% potassium hydroxide cleared lesion scrapings reveal typical, thick-walled, cigar-colored, sclerotic cells, also known as Medlar bodies, are readily seen.

A

Chromomycosis

61
Q

Copper pennies on histology

A

Chromomycosis