DNA Viruses Flashcards

1
Q

DNA Viruses

A
HHAPPPy
Hepa B
Herpes
Adeno
Pox
Papo
Parvo
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2
Q

All DNA viruses are double stranded except

A

Parvo

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3
Q

All DNA viruses are icosahedral except

A

Pox

Complex

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4
Q

All DNA viruses replicate in the nucleus except

A

Pox

Cytoplasm

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5
Q

Naked DNA viruses

A

Papo
Adeno
Parvo

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6
Q

Naked DNA virus without vaccine

A

Parvovirus B19

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7
Q

Oncogenic naked DNA virus

A

HPV

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8
Q

Slapped cheeks which does not spare nasolabial fold
Fever
Coryza
Sore throat

A
Erythema infectiosum (fifth disease)
Parvovirus B19
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9
Q

Pancytopenia in immunodeficient patients

A

Chronic B19 infection

Parvo

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10
Q

1st trimester fetal death

2nd trimester hydrops fetalis

A

Parvovirus B19

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11
Q

Transient but severe aplastic anemia in children with sickle cell anemia, thalassemia or spherocytosis

A

Aplastic crisis

Parvovirus B19

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12
Q

Only virus with PENTONFIBERS

A

Adenovirus

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13
Q
DNA virus
Double stranded
Naked
Icosahedral
Linear
A

Adeno

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14
Q

Conjunctivitis

Hemorrhagic cystitis

A

Adeno

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15
Q

Cowdry type B inclusions

Intranuclear

A

Adeno

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16
Q
DNA virus
Double stranded
Naked
Icosahedral
Circular
A

Papo

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17
Q

Papovaviridae

A

HPV
JC polyoma
BK polyoma

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18
Q

Pinkly stained with cytoplasmic bleb/vacuole

A

Koilocyte
HPV
Papo

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19
Q

E6 and E7

Malignant transformation

A

HPV

Papo

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20
Q

HPV
Skin and plantar warts
Condyloma acuminata and respiratory tract papillomas
Carcinoma

A

1-4
6 and 11
16 18 31 33

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21
Q

Most common viral STD

A

HPV 6 and 11

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22
Q

HPV
Skin warts
Plantar warts
Condyloma acuminata

A

Liquid nitrogen
Salicylic acid
Podophyllin

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23
Q

Progressive multifocal leukoencephalopathy in AIDS patients

A

JC Polyoma Virus

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24
Q

Hemorrhagic cystitis and nephropathy in patients with solid and BM transplants

A

BK polyoma virus

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25
``` DNA virus Double stranded Enveloped Complex Linear ```
Pox
26
Poxviridae
Variola smallpox | MCV
27
Brick shaped poxvirus containing linear dsDNA
Variola virus | Smallpox
28
Largest viruses
Variola virus | Smallpox
29
Guarnieri bodies | Intracytoplasmic eosinophilic inclusions
Variola virus | Smallpox
30
Eradicated disease
Variola virus | Smallpox
31
Pinkish papular skin lesions with an umbilicated center
MCV | Cifodovir
32
Henderson Peterson bodies | Intracytoplasmic eosinophilic inclusions
MCV | Cifodovir
33
``` DNA virus Double stranded Enveloped Icosahedral Linear ```
Herpes
34
Herpesviridae
``` HSV VZV CMV EBV HH8 ```
35
HSV1 | HSV2
Saliva or direct above umbilicus | Sexual or transvaginal below umbilicus
36
HSV1 | HSV2
Trigeminal ganglia | Lumbosacral ganglia
37
HSV Microscopy
Multinucleated giant cells on TZANCK SMEAR COWDRY TYPE A (ZVZ)
38
DOC for HSV
Acyclovir
39
VZV | Latent in the _
Dorsal root ganglion
40
Vesicular centrifugal rash with DREWDROP ON A ROSE PETAL appearance
Varicella
41
Aspirin in pediatric diseases
Kawasaki ARF JRA
42
Painful vesicles along dermatomal distribution | Postheroetic neuralgia
Zoster
43
Involvement of geniculate ganglion causes facial nerve paralysis
Ramsay Hunt Syndrome
44
DOC for ZVZ
Acyclovir
45
Cultured in shell tubes
CMV
46
Heterophil Negative Positive
CMV | EBV
47
Immediate early proteins that impair assembly of MHC Class I
CMV
48
Giant cells with OWL'S EYE nuclear inclusion
CMV
49
``` Microcephaly Seizures Deafness Jaundice Purpura 1st trimester infection ```
Congenital CMV infection
50
Most common cause of blindness in HIV
Systemic CMV infections | Foscarnet
51
DOC for CMV
Ganciclovir
52
Kissing disease
Infectious Mononucleosis | EBV
53
Downy cells
Infectious mononucleosis | EBV
54
EBV malignancies
Burkitt's lymphoma african NPCA chinese Hairy leukoplakia AIDS B cell lymphoma
55
Dark purple flat to nodular skin lesions at multiple sites in AIDS patients
Kaposi's sarcoma | HH8
56
``` DNA virus Double stranded Enveloped Icosahedral Circular INCOMPLETE ```
Hepa B
57
Hepatitis symptomatologu
A asymptomatic B blood C chronic cirrhosis carcinoma carriers E enteric expectant mothers epidemics Vowels A and E hit your bowels
58
Marker for viral replication | Hep B
HBcAg | HBeAg
59
Only DNA virus that produces DNA by reverse transcription
Hep B
60
T or F | HBV has numerous cytopathic effects
No | Liver injury due to immune attack
61
Hep B | Incubation period
HBsAg + Anti HBs - Anti HBc - HBe Ag + Incubation so no Ab yet
62
Hep B | Acute infection
HBsAg + Anti HBs - Anti HBc POSITIVE IGM HBe Ag +
63
Hep B | Window period
HBsAg - Anti HBs - Anti HBc POSITIVE IGM HBe Ag -
64
Hep B | Complete recovery
HBsAg - Anti HBs + Anti HBc POSITIVE IgG HBe Ag -
65
Hep B Chronic carrier >6 months
HBsAg + Anti HBs - Anti HBc POSITIVE IgG HBe Ag -
66
Hep B | Chronic active
HBsAg + Anti HBs - Anti HBc POSITIVE IgG HBe Ag +
67
Hep B | Vaccinated
HBsAg - Anti HBs + Anti HBc - HBe Ag -
68
``` Dark urine Pale feces Elevated transamine levels Hepatocellular carcinoma Polyarteritis nodosa ```
Hep B
69
Conplications of Hep B
Hepatorenal functional renal failure | Hepatopulmonary overperfusion
70
DOC for Hep B
Lamivudine | Interferon A
71
First vaccine to prevent human cancer
Hep B
72
``` DNA virus Single stranded Naked Icosahedral Linear ```
Parvo
73
Vaccinia
First live virus vaccine | Smallpox
74
DNA Virus transmitted through breast milk
CMV