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Microbiology 2 > Mycobacteria > Flashcards

Mycobacteria Flashcards

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0
Q

Luciferase assay for drug resistance

A

Mycobacterium tuberculosis

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1
Q

Ziehl Neelsen
Kinyoun
Slow growing on Lowenstein Jensen medium

A

Mycobacterium tuberculosis

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2
Q

Most important virulence factor of Mycobacterium tuberculosis

A

Cord factor

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3
Q

Tuberculin surface protein

A

Delayed hypersensitivity

M tb

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4
Q

Exported repetitive protein

A

Sulfatides
Prevent phagosome-lysosomal fusion
M tb

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5
Q

Ghon’s focus in middle or lower lobes

Ranke’s complex

A

Primary TB

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6
Q

Simon’s focus in apices

Cicatricial changes, subpleural blebs, cavitation

A

Reactivation tb

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7
Q

PPD
_ mm for HIV/AIDS, ICC, old TB
_ mm for HR population
_ mm for LR population

A

5
10
15

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8
Q

New smear positive
New smear negative with extensive disease
New severe extrapulmonary TB

A

2 HRZE

4 HR

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9
Q

Sputum smear positive

Relapse, treatment failure, defaulter

A

2 HRZES
1 HRZE
5 HRE

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10
Q

New smear negative other than category I

New less severe extrapulmonary disease

A

2 HRZE

4 HR

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11
Q

BCG Vaccine

A

Limit extent of the disease

Treatment of bladder cancer

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12
Q

Pulmonary disease in ICC hosts

A

MAC

Azithromycin

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13
Q

M leprae is transmitted by prolonged exposure to _ of patients with lepromatous form.

A

Nasal secretions

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14
Q 
Few hypopigmented anesthetic plaques and thickened superficial nerves
Little tissue destruction
Few number of AFB
Low transmission
Present cell mediated response
Postive lepromin skin test
A

Tuberculoid leprosy

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15
Q 
Leonine facies
Erythema nodosum leprosum
Marked tissue destruction
High number of AFB
High transmission
Negative lepromin skin test
A

Lepromatous leprosy

16
Q

Red snappers on microscopy

A

M leprae

17
Q

DOC for
Tuberculoid leprosy
Lepromatous leprosy

A

Dapsone Rifampin

Dapsone Rifampin clofazimine

18
Q

Treatment for erythema nodosum leprosum is associated with this congenital malformation

A

Thalidomide

Phocomelia

Microbiology 2 (13 decks)

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