Spine Flashcards

1
Q

Sections of the Spine ?

A

Cervical - C1 - C7

Thoracic - 12 bones

Lumbar - 5 - L1 - L5

Sacrum - 5 ( fused )

Coccyx - 4 (fused)

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2
Q

Structure of spine a vertebrae ?

A

2 major parts : Vertebral body and arch.

  1. Vertebral body - anterior part
    * the weight bearing part. Vertebral bodies get larger as you go down the spine.

Adjacent bodies separated by fibrocartilaginous intervertebral disc.

  1. Vertebral arch - posterior aspect.

Has bony prominences - attachment for muscles/ ligaments

The vertebral body + arch - leaves a hole in the middle - forearm -
* When all the bodies and arches line up form the vertebral canal - encloses the spinal cord.

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3
Q

Structure of the vertebrae - different sections of the spine ?

A

Cervical - C1 - C7
3 FEATURES :
0 Bifid Spinous process

0 Transverse foramina

0 Triangular foramen.

(C1 - no spinous process
C7 - spinous process - may not bifurcate . )

Thoracic -

have 2 demi facets and costal facet.

Circular vertebral foramen.

Lumbar-

Kidney shaped
Vertebral bodies - very large.

Triangular foramen.

  • size and orientation allow for needle access not possible in other section e.g. lumbar puncture , epidural anaesthesia administration.

Coccyx - has no veterbral arches thus no vertebral canal.

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4
Q

congenital abnormalities

A

sacralisation

lumbarisation

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5
Q

Abnormal morpholgy of the spine

A

Kyphosis - excessive thoracic curvature- hunchback defomity

lordosis - excessive lumbar curvature - sawyback deformity

scolosis - lateral curvature of spine

cervical spondylosis.- decreased size of IV foramen- narrows IV foramina - put pressure on nerves passing through

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6
Q

What is three column concept .

A

A way of describing & diagnosing spinal fractures.

0 Anterior column 
     - Anterior 
      Longitudinal 
      ligament
     - Anterior 
       disc
     - Anterior 
       half of 
       vertebral 
       body. 
0 Middle column
 - same as anterior just replace anterior with posterior. 

0 Posterior column

  • Spinous P
  • Pedicels
  • Lamina
  • Ligamentum Flavum
  • Interspinous & Supraspinous L
  • Superior and inferior articulating P.

IMPORTANT - Fracture is unstable if it affect 2 adjacent columns e.g anterior & middle or middle & posterior. Also, if all three are.

Considered stable - if one affected.

exception - Bilateral pedicle fracture - Happens in posterior column, however effects the other columns (pedicles - connect

STABLE - do not cause spinal deformity or nerve problems . Can still distribute weight well.

UNSTABLE - opposite of stable.

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7
Q

What is a burst fracture ?

A

Burst fracture - Axial loading injury - disc above is pushed into the IV disc pushed into veterbral body below.
( discs crushed / compressed against each other due to pressure - causing spreading fractures )

Vertebrae break in multiple direction and can cause damage to spinal cord.
(greater the force applied , the more fragaments may be forced into spinal canal and damage the spinal cord - nerve damage - possible paralysis depending on severity

  • occur usually from severe trauma - motorcycle accident , fall from height.

Typically - in the back - will complain of severe back pain - if had accident lie patient flat don’t sit them up of flex back - worsen neurological injury. Also complain of Lower limb neurological deficits

Patient may not be also wot walk after injury - if they can should still avoid to avoid further injury.

Summary - clincal presentation when trauma involved

  • severe back pain
  • lower limb deficits.
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8
Q

Types of Spinal Fractures ?

A

0 Burst Fracture

0 Veterbral compression fracture

0 Fracture - dislocation

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9
Q

management of Burst fracture ?

A

CT scan - evaluate extent of retro pulsed fragments - ( retro pulsed fragments
vertebral fragment which has been displaced into spinal canal - potential spinal cord injury.)

Radiological investigation - may see :

0 loss of veterbral height from lateral view - anterior portion of veterbral body compressed more than posterior.

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10
Q

What is a Fracture- dislocation fracture ?

A

Involves displacement - Vetebrae moves off adjacent veterbrae. ——> often cause serious spinal cord compression.

Occur secondary to high energy trauma ( e.g motorcycle accident.

Unstable and high risk of spinal cord injury.

  • complete fracture - dislocation often result in severe neurological injury causing lower extremity weakness & decreased sensation.
  • seems to usually occur in Thoracolumbar spine and usually involve all 3 columns - unstable.
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11
Q

What the 3 Spinal fracture patterns ?

A

0 Flexion fracture pattern :

Compression fractures - compression causes breaking of veterbrae bone ( osteoporosis & trauma)

Axial burst fractures - high eneegy trauma - parts of vetebrae shatter - more severe than compression farctures - can cause long term neurological damage.

0 Externsion FP - veterbrae pulled apart (e.g seat belt injury - in a head on car accdient the seat belt keeps lower body in place while upper body thrust forward. )

0 Rotation
- e.g Transverse frcature - cause by extreme rotation or sideways bending.

  • fracture - disloaction - vetebrae displaced - compressing spinal cord.
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12
Q

What is veterbral compression fracture ?

A

Vetebral body ins spine collaspses causing loss of height , deformity and severe pain.

CAUSES -

  1. Osteoporosis

Most common fracture in patients with osteoporosis - caused by falling down or trauma.

  • if severe osteoporosis - fracture can be ccaused by simple daily task (e.g sneezing forcelly , liftinh heavy object - no traumatic accident)
  • also effect postmenapausal women.
  • People with Osteporotic VCF more likely to get a second.
  1. Cancer -
    metastic cancers/ tumours - cancer spreads to bone and causes destruction of veterbrae. - weakening bone.
  2. Severe trauma - healthy spine - car accidents etc.
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13
Q

Symptoms of VCF ?

A

0 Sudden onset of back pain

0 An increase of pain intensity while standing or walking

0 A decrease in pain intensity while lying on the back

0 Limited spinal mobility

0 Eventual height loss

0 Eventual deformity and disability

  • Acute VCF - pain is usually well localised to midline
  • Chronic VCF - progressive loss of height
  • numerous VCF - causes curvature of spine (Hyperkyposis)
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14
Q

What is veterbral compression fracture ?

A

Vetebral body in spine collaspses causing loss of height , deformity and severe pain.

CAUSES -

  1. Osteoporosis

Most common fracture in patients with osteoporosis - caused by falling down or trauma.

  • if severe osteoporosis - fracture can be ccaused by simple daily task (e.g sneezing forcelly , lifting heavy object - no traumatic accident)
  • also effect postmenapausal women.
  • People with Osteporotic VCF more likely to geta second.
  1. Cancer -
    metastic cancers/ tumours - cancer spreads to bone and causes destruction of veterbrae. - weakening bone.
  2. Severe trauma - healthy spine - car accidentss etc.
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15
Q

Treatment of VCF ?

A

Analgesics - pain relief

Physical therpay - early mobilisation - to prevent further bone loss and disability.
( may be delayed if pain not controlled )

if Osteoporosis present - treat e.g biphosphonate.

Bracing

Diagnosis -

X - ray - if osteoporotic fractures
0 Loss of vertebral height (particularly >
6 cm or more than half the height of
the vertebral body)
0 Decreased radiodensity
Loss of trabecular structure
0 Anterior wedging

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16
Q

What is Spondylolisthesis ?

A

Spondyl - condition of Vetebrae

Listhesis - slipping

Condtion - one vetebrae slides forward over the veterbrae below it.

4 grades

  • Grade 1 - 0 -25 % sublaxation -
  • Grdae 2 - 25 -50 % sublaxation )
  • Grade 3 - 50 - 75 % sublaxation )
  • Grade 4 - 75 - 100 % (sublaxation )

*Sublaxation - partial dislocation

17
Q

What is Spondylolisthesis ?

CAUSES - TYPES

GRADES

A

Spondyl - condition of Vetebrae

Listhesis - slipping

Condtion - one vetebrae slides forward over the veterbrae below it.

4 grades

  • Grade 1 - 0 -25 % sublaxation - spillage
  • Grade 2 - 25 -50 % sublaxation )
  • Grade 3 - 50 - 75 % sublaxation )
  • Grade 4 - 75 - 100 % (sublaxation )

*Sublaxation - incomplete / partial dislocation

sub - below
laxation - to dislocate

  • common in lumbar spine

CAUSES

0 Type 1 - congenital: caused by agenesis (failure / lack of development ) of superior articular facet.

0 Type 2 - isthmic: caused by a defect in the pars interarticularis( part of vetebrae inbetween inferior and superior artcular process )- causes (spondylolysis)

0 Type 3 - degenerative: caused by articular degeneration( degeneration of articular cartlage ) as occurs in conjunction with osteoarthritis.

0 Type 4 - traumatic: caused by fracture, dislocation, or other injury

0 Type 5 - pathologic: caused by infection, cancer, or other bony abnormalities

  • TYPE 1 AND 2 most common
18
Q

Treatment of Spondylolisthesis ?

A

Physical therapy

Lumbar stabilisation.

plain x ray.

19
Q

What is Whiplash ?

A

Head forcibly hyperextended - occurs car collsion -head rest poorly positioned.

Usually effects soft tissue - soft tissue injury.

Severe whiplash can cause fractures.

Hyperextended - anterior longitudinal ligament
( head is moved backwards - angle btween chest and head increases - neck extended )

( if head was hyperflexed - nuchal ligament - extends from external occipital protubernace to spinous P of C7, - Supraspinous ligament takes over - nuchal and supraspinous L are continous )

most likely damaged )
( head moves forward - angle btw head and chest decrease - length of neck decreases.

20
Q

What is Spinal herniation ?

What is it ? , causes ? , Stages - brief ?

A

Nucleus Pulpsus herniates through weakness/ tear in Annulus Fibrosus. NP displaced posterolaterally /posteriorly into extradural space.

0 Nucleus Pulposus ( NP) - inner core of the veterbral disc.
0 Annulus Fibrosus surrounds - tough exterior of the inveterbral disc - surrounds NP
0 Endplate - the interface btw the IV disc & veterbrae.

CAUSES

0 violent Hyperflexion + Annulus Fibrosus degeneration - disc rupture -
disc compressed anteriorly , posterior section of disc is stretched , NP squeezed posteriorly towards thin part of Annulus Fibrosus.( herniation will occur if if AF degenerated )

4 stages
0 Degenerating disc 
0 Protrusion
0 Extrusion 
0 Sequestration.
21
Q

Stages of Herniation - spine ?

A

0 Disc degeneration - AF damaged / weak / torn due injury - NP unable to retain as much fluid so decreased thickness of disc.

0 Protrusion - Nuclues Pulposus impinges ( encoarches/ obtrude into ) Annular Fibrosus - Posterior Longitundinal ligament remains intact.

0 Extrusion - NP emerges through AF. PLL intact. ( still within disc )

0 Sequestration - PLL is disrupted + portion of NP protuded into epidural space.

  • (Epidural speace - btw dura matter and veterbral wall )
22
Q

Consquences of Spinal herniation ?

A

symptoms depend on dermatome effected

Most herniation happen in lumbar region - as age herniation can occur at higher levels - as degradation occurs

0 Compression of nerve in the interveterbral foramen.

0 Radiculopathy - compression of nerve route causes pain + weakness of muscles in the myotome it supplies.
SYMPTOMS - pain ,weakness ,
numbness & tingling ( Paraesthesia -
pins and needles ) , anaesthesia -
loss of sensation .

0 Referred pain - pain felt in the dermatome which is supplied by the compressed nerve route.

0 Localised acute pain where disc is herniated - pain caused by pressure on ligaments & AF & inflammation ( due to ruptured NP causing chemical irritation)

23
Q

What are myotomes ?

important ones ?

A

Myotome - group of muscles innervated by a single nerve route

C4: shoulder shrugs
C5: shoulder abduction and external rotation; elbow flexion
C6: wrist extension
C7: elbow extension and wrist flexion
C8: thumb extension and finger flexion
T1: finger abduction
L2: hip flexion
L3: knee extension
L4: ankle dorsiflexion
L5: big toe extension
S1: ankle plantarflexion
S4: bladder and rectum motor supply
24
Q

What is Sciatica ?

A

Sciatica - Pain down the sciatic nerve
can be refererred to Lumbar radiculpathy - nerve root compression causing pain , tingling & numbness , irritation in lumbarsacral spine,

SYMPTOMS

Extend from buttocks —-> back of thigh ——-> outer calf ——-> sometimes to foot and toes.

( sciatic nerve - L4 -S3 - innervates muscles of posterior thigh , hamstring portion , indirectly innervates all muscles of leg and foot )

CAUSES
0 Herniated IV disc - 90 % of time
0 spondylolithesis
0 spinal stenosis

Treatment

0 Urgent referral symtoms

  • signs of Cauda equina syndrome
  • Spinal fracture
  • cancer
  • signs of infection

offer analegesia - manage low back pain
Group excercise , physiotherapy

  • stop opiods , gabapentinoids , benxodiazepines , corticosteriods , antiepileptics .
25
Q

What is lumbar puncture ?

A

Lumbar puncture / spinal tap

Aim - sample CSF in subarachnoid space ( between arachnoid and pia mater )

Thin needle - inserted either btw L3 -L4 or L4 - L5
BELOW L2 - TO AVOID PUNCTURING SPINAL CORD

26
Q

Contraindication of Lumbar puncture ?

A

0 Raised Intercranial pressure
- reduced or flucuating GCS - below 9 or drop of more three three

  • uequal , dilated , or poorly responsive pupils
  • papilloedema
  • relative bradycardia and hypertension
  • focal neurological signs
  • abnormal posture or posturing
    etc.

Shock

0 Convulsions - need to stabilise

0 coagulation abnormalities 
     - Blood outside normal 
     - on 
 anticoagulant therapy 
- platelet count below 100×109/litre

0 superficial infection at the lumbar puncture site

0 respiratory insufficiency (high risk of precipitating respiratory failure in the presence of respiratory insufficiency)

0extensive / spreading Pupura - blood spots /skin haemorrages - reddish- purple coloured
(blood vessels burst & pooled under skin ) - a sign of blood clotting disorder but can be benign.

27
Q

Indications of Lumbar puncture ?

A

Diagnostic & therapetic

0 Cerebrospinal fluid analysis (i.e. meningitis,
- suspicion of Meningitis

0 multiple sclerosis,

0 subarachnoid haemorrhage)

0 Spinal epidural (i.e. during labour)

0 Spinal medications (i.e. analgesia, chemotherapy, antibiotics)

0 Fluid removal (i.e. to reduce intracranial pressure)

28
Q

Leg pain

A

nerve or blood vessel pain

when you bend forwards - makes it work , more relief when you bend spine

vessel pain - ischemic -worse with physical activity/ n excretion - oxygen demand increased.

29
Q

What is ankylosing spondylitis ?- adults

Character
Risk factors
Diagnosis

A

Ankylosing spondylitis - form of ongoing joint inflammation (chronic inflammatory arthritis) that primarily affects thespine.

CHARACTER
Primarily affects sacroiliac joints and axial spine.

  • back pain and stiffness .
  • Vertabrae fusion over time, back movement gradually becomes limited.
  • progressive bony fusion is called ankylosis.

-inflammatory back pain (Inflammatory back pain is the hallmark clinical feature. This is defined as back pain that is of insidious (gradual & cumulative) onset, is worse in the morning, and improves with exercise.)

iritis/uveitis - extra- articular inflammation can cause this

RISK FACTORS

enthesitis (Inflammation of joint)

presentation in late teens and early 20s

DIAGNOSIS

O pelvic x ray ( includes lower spine) - Sacrolitis present - bamboo spine (fusion)

Possible ones 
- spine x tay 
Cervical
Lumbar
Thoracic 

-MRI

HLA-B27 is present in about 90% of patients who have AS.[32

male sex

positive family history of AS

30
Q

Treatmemt of ankylosing spondylitis?

A

ADULTS - PAIN OR STIFFNESS

1ST LINE

NSAIDS + non pharmacological intervention ( supervisee physiotherapy)

Adjunct - analgesics ( 1st - para , 2nd codeine)

If peripheral joint involved( joint other than spine )

PLUS - methotrexate or sulfasalazine

If local intra articular involvement

PLUS - intra- articular corticosteroids.

ADULT - Without pain and/or stiffness

Patients with a diagnosis of AS but without spinal pain and/or stiffness should be reviewed to confirm a definite diagnosis of AS.

REFACTORY TO 2 NSAIDS

1ST LINE

Tumour necrosis factor alpha inhibitor + physiotherapy

-etanercept

OR

infliximab
Golimumab
Cetrolizumab

OR

adalimumab

2ND LINE

0 another TNF alpha inhibitor + physiotherapy or interleukin 17 inhibitor e.g.
secukinumab
ixekizumab

All lines of treatment NSAIDS use should be continued .

31
Q

What is ankylosing spondylitis ? - child

A

Oligoathritis (1-5 joints)

1st line

0 NSAIDS + Non pharmacological intervention

Plus- intra articular corticosteroids

Polyathritis (more than 5)

0 Sulfasalazine + non pharmacological intervention

Enthesitis and/or peripheral athritis.

0 Tumour necrosis factor alpha inhibitor + non pharmacological intervention

-etanercept

OR

infliximab

OR

adalimumab