soft tissue infection Flashcards

1
Q

what is cellulitis

A

red deep infection

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2
Q

what is ecythema

A

crusty deep lesion

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3
Q

what is impetigo

A

superifical crusty lesion

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4
Q

what is erysipelas

A

superficial red patch that has very clear boundaries

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5
Q

what causes impetigo

A

either s.aureus or s.pyogenes

-very contaigous

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6
Q

what causes ecthyma

A

also s.aurues and s.pyogenes but deeper form into dermis

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7
Q

what causes ecthyma gangrenosum

A

pseudomonas aeruginosa

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8
Q

causes of cellulitis

A

s.aureus or beta haem strep

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9
Q

what is erysipelas caused by

A

group a beta haem strep pyogenes

  • lypmatics
  • distinct borders
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10
Q

what is a furuncle

A

deep folliculitis of one hair follicle also called a boile

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11
Q

what causes furuncles

A

s.aurues

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12
Q

what is a carbuncle

A

multiple hair follicles infected and systemic upset possible

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13
Q

what is erysipeloid

A

dermatitis of the hand due to a bacterial infection

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14
Q

what causes necrotising fasciitis

A

monomicrobial usually s.pyogenes

polymicrobial with s.aureus

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15
Q

clinical features of nec fasciitis

A
  • pain that is out of proportion or unrequitting
    skin necrosis
    multi-organ failure
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16
Q

treatment nec fasci

A
  • ben pen
  • fluxoc
  • clinda
  • metro
  • genta
17
Q

what causes gas gangrene

A

clostridium perfringens

18
Q

what is fournier’s gangrene

A

type of necrotising fasciitis affecting external genitalia or perineum

19
Q

what causes toxic shock

A

s. pyogenes

s. aureus

20
Q

what causes myonecrosis

A

clostridium perfringens

21
Q

risk factors for clostridium ssti

A
  • wound contaminantion

- IVDU spores

22
Q

risk factor for ecthyma gangrene

A

water or hot tub

23
Q

what does virbrio vulnificus cause and risk factor

A

-gas ganrene

due to saltwater, fish handling

24
Q

where is aeromonas hydrophila infection

A

fresh water

25
Q

what causes pasteruella infection

A

dog, cat bite or wound

26
Q

what causes erysipelothix rhysopathiae infection

A

puncture wound

shrimp or crab

27
Q

what is sirs

A

systemic inflammatory response

28
Q

what is septic shock

A

SIRS plus infection

29
Q

SIRS criteria

A
two or more of
temp >38 or <36
hr >90
rr>20
wcc >12 or <4
30
Q

how does cellulitis go to nec fasciitis

A

o Hyperinflammation
o Bacterial burden-intracellular survival-bacterial enzymes/ exotoxin- direct tissue destruction
o Neutrophil predominant
o Pro-inflammatory cytokine millieu (IL-1, TNFb, IFN Y)-neutrophil degranulation
o Microvascular thrombosis
o T cell migration-further amplification
o Dysregulation of the immune response
o Overwhelming sepsis-immune regulatory mechanisms overpowered
-inappropriate response

31
Q

test for nec fasciitis

A

if run finger over produces immense pain woody tissue

32
Q

imetigo treatment

A

fluxoc

33
Q

erysipelas (strep_ treat

A

fluxoc

amoxi

34
Q

mssa cellulitis

A

flucox

35
Q

mrsa cellulitis

A

vancomycin

36
Q

how long isolation for group a strep

A

minimum 24 hours

37
Q

difference recurrent cellulitis in strep and s.aureus

A

strep=previous site

s.aureus=different site