soft tissue

Question 1

tendonitis vs -osis

Answer 1

Tendinitis = acutely inflamed swollen tendon that does not have microscopic tendon damage
Tendinosis = chronically damaged tendon characterised by disorganised fibres and a hard, thickened, scared and rubbery appearance

Question 2

unexpected cause of tendonitis and MOA

Answer 2

renal dialysis, poss use of steroids messing up collagen production

Question 3

what do see here in this previously damaged achilles tendon

Answer 3

heterotopic calcification

Question 4

which procedure is often associated with heterotopic ossification and what is the tx

Answer 4

hip replacement
prophylactic NSAIDS

Question 5

describe the 4 phases of tendon healing

Answer 5

Question 6

what is a fibrous enthesis

Answer 6

Fibrous tissue extends all way up to bone

Question 7

what is a fibrocartilaginous enthesis

Answer 7

Question 8

3 examples of fibrocartilagenous enthesis

Answer 8

rotator cuff muscles, Achilles tendon, plantar fascia

Question 9

what happens at a fibrous enthesis?

Answer 9

collagenous Sharpey fibres pierce through periosteum to attach tendon to the bone

Question 10

what sort of enthesis is this

Answer 10

fibrocartilagenous

Question 11

gene associated with ankylysing spondylitis

Answer 11

HLA-B27

Question 12

what is an enthesophyte

Answer 12

tendon gets damaged and repalced with bone which protrudes outwards making a bone spur

Question 13

which IL associated with enthetitis

Answer 13

IL23

Question 14

tnf alpha inhibitor

Answer 14

infliximab

Question 15

tx for autoimmune musculoskeletal conditions

Answer 15

methotrexate
sulfasalazine
infliximab

Question 16

what can you inject into an enthesitis to promote healing

Answer 16

hyperosmolar dextrose

Question 17

tendonitis vs enthesitis

Answer 17

in the tendon

at the insertion point

Question 18

ouchy snuff box, new mothers

Answer 18

De Quervain’s tenosynovitis

Question 19

test for de quervain’s

Answer 19

pull thumb side away from forearm. positive is pain

Question 20

what causes trigger finger

Answer 20

tendon enlargement inside the sheath

Question 21

what is SLE

Answer 21

Systemic lupus erythematosus

Question 22

SLE classic presentation

Answer 22

butterfly malar rash on face

Question 23

symptoms of lupus

Answer 23

Nonspecific fatigue, fever, arthralgia weight changes, and dermatological
Small joints of hands, wrist and knees
Migratory asymmetrical pain not related to swelling
Malar facial rash in butterfly pattern
Photosensitivity
Discoid lesions
Alopecia
Renal nephritic disease
Neuropsychiatric
Pulmonary
Gastrointestinal
Cardiac
Hematologic

Question 24

what has the problem in SLE arthritis and what is the consequence. what is the name

Answer 24

the tendon sheaths (not the bones) - it can be reversed. Jaccoud arthroptahy

Question 25

which antibodies in SLE

Answer 25

ANA

Question 26

what does DMARD mean

Answer 26

Disease-modifying antirheumatic drugs

Question 27

SLE mab which isn’t rituximab. MOA

Answer 27

belimumab - anti BAFF (B cell activating factor)