gout Flashcards
which crystals in gout
monosodium urate
monosodium urate crystals are normally coated in…
proteins eg albumin
what causes a gout attack
UNCOATED monosodium urate crystals which then become visible to the body
what shape are monosodium urate crystals
needle-like
main cytokine in gout
IL-1
what do you see here
rat-bite erosions. Chronic gout
what are gout bumps called
tophi
what colour is synovial fluid in gout
white and cloudy
allopurinol moa
inhibits xanthine oxidase
rasburicase moa
catalyses uric acid to allantoin which is more soluble
what is pseudogout
calcium pyrophosphate depositions in joints
what shape crystals in pseudogout
rhomboid
what presentation pseudogout
most pts asymptomatic
what can you see here in the meniscus
chondrocalcinosis (extra white line)
can you see uric acid crystals in H and E
no
compare gout vs pseudogout
what is this
cholesterol plate deposits in a joint
