pain Flashcards
which fibres pain heat
C
which inflammatory mediators enhance peripheral nociception
(K+ H+ bradykinin, histamine, 5HT, nitric oxide
what is nociplastic pain
pain with no stimulus - caused by the brain over-sensitity to nociception
Activation of arachidonic acid pathway leads to
production of leukotrienes and prostanoids
when you have a nerve damage, where do you perseive the neiropathic pain
at the distal end
what is ephaptic conduction
when neurones accidnetally conduct from each other
allodynia vs dysaesthesia
a is sign
d is symptom
time margin acute vs chronic pain
12 weeks
anti-neuropathic agents moa, example,
membrane stabilisers, binds to alpha-2 delta Ca channel, pregabalin, gabapentin
anti-neuropathic diabetic pain drug
duloxetine
Jo Cameron molecule
anandamide
NOS other use
analgesia
