SNS Blocker Alpha 1 Blockers

Question 1

What is the action?

Answer 1

blocks alpha 1 receptor sites

↓ vascular tone = vasodilation ↓ BP

Question 2

SNS blocker Alpha 1 blocker drug names?

Hint: end in “azosin”

Answer 2

Doxazosin
Prozosin
Terazosin

Question 3

What are the contraindications/cautions?

Answer 3

Allergy
Heart Failure
Renal Failure
Hepatic impairment

Question 4

what are the drug-drug interactions (DDI)?

Answer 4

Vasodilators/antihypertensives

Question 5

What are the indications (use for)?

Answer 5

HTN

BPH (Benign Prosthetic Hypertrophy)

Question 6

What are the adverse effects?

Answer 6

CNS: Headache, weakness, Dizziness, Fatigue
CV: Hypotension, arrhythmias, edema, heart failure, angina
GI effects: N & V, abdominal pain
GU effects: Priapism (prolonged erection; ER visit, get blood drawn out)

Question 7

What are the nursing implications?

Answer 7

Hx: contraindication/cautions
CNS: cardiac, respiratory, abdominal, urinary, perfusion
Vitals, ECG
Labs: electrolytes, renal/hepatic function, glucose
Take apical pulse; hold if below 60
Monitor blood glucose
Lifestyle changes
change position slowly
Do not crush extended-release formulations