Renin Inhibitor Flashcards
1
Q
What is the action of Renin Inhibitor?
A
prevents renin from being released; inhibits RAAS;
↓ BP; ↓ aldosterone; ↓ sodium reabsorption (pee more water and sodium)
2
Q
Renin inhibitor drug name?
A
Aliskiren
3
Q
What are the contraindications of Renin inhibitor?
A
Pregnancy
4
Q
What is the indication (use for) for Renin inhibitor?
A
HTN
5
Q
What are the drug-drug interactions (DDI) of Renin inhibitor?
A
Furosemide (↓ diuretic effect)
other drugs affecting the RAAS ACE & ARBs (↓ Blood flow to the kidney)
6
Q
What are the adverse effects for Renin inhibitors?
A
Hyperkalemia (↑ potassium due to ↓ aldosterone release)
7
Q
What are the nursing implications for Renin inhibitors?
A
Impaired kidney function Salt/volume depletion Vitals & weight Labs: renal fxn tests, electrolytes, & pregnancy test life style changes use barrier contraceptives ↓ fluid volume, dehydration, vomiting, & diarrhea response to drug
