Smell Flashcards
odor
the translation of a chemical stimulus to smell sensation
odorant
the actual molecule(s) that capable of being translated into smell
odorants must be (3 things)
volatile (able to float through air)
small
hydrophobic (repellent to water)
you don’t smell ___ despite it constantly filling your nose qualifying
air
not perceiving particular odorants may be a mix of (3 things)
evolution, genetics, habituation
primary purpose of your nose
to let you breathe while filtering and warming that air
2 paths for air/olfaction
orthonasal
- direct to your nasal passage, what you use to sniff
retronasal
- odorants pass from your throat back up to your nasal passage
olfactory cleft
a narrow space at the back of the nose where air and odorants flows
olfactory epithelium
a mucous membrane in the cleft that detects odorants in the air
transduction happens here
3 cell types in the olfactory epithelium
olfactory sensory neurons (OSNs)
- transductors
supporting cells
- metabolic and physical support
basal cells
- cells that will eventually become OSNs
OSNs have cilia as well, defined as …
extend surface area for chemical receptors that odorants can bind to
you need _____ molecules/odorants binding to a receptor to initiate an action potential
several!
axons from OSNs pass through bony _______ _____ and form olfactory nerves (cranial nerve I)
cribriform plate
after the cribriform plate, the smell pathway continues in the ____ _____
olfactory bulbs
olfactory bulbs
one per side of nose and brain
ipsilateral
anosmia
the loss of smell
OSNs converge on ________ based on shared receptor types in the olfactory bulb
glomeruli
rule of 1-1-1
each OSN has 1 receptor type, which responds to 1 odorant, and all of that type converge on 1 glomerulus
despite the 1-1-1 rule and only 1000 receptor types, we can detect over ________ smells
one trillion
without a particular receptor, or if it becomes faulty, can have _____ ______ for that odorant
specific anosmia
general order in depth (shallow to deep) for later olfactory bulb cells is…
tufted –> mitral –> granule