small vessel vasculitis Flashcards
Wegener Granulomatosis presentation
Hemoptosis (coughing up blood)
Hematuria (peeing blood)
WEgener Granulomatosis affects which organs?
lungs
kidneys
URT
What is the pathology of Wegeners
necrotizing vasculitis,
granulomatous vasculitis,
crescentic glomerulonephritis
How will a pt. present with wegeners
usually a male with URI, saddle nose, peeing blood, pronteinuria, necrotizing on face
Churg-Strauss syndrome presents with a philia of which cell type?
eosinophilia
pathologic findings include granulomas and fibrinoid necrosis
What particular respiratory issue will a person with Churg-Strauss present with?
Asthma or allergy
What ANCA assoc with Churg-Strauss
MPO-ANCA
how do yuo treat Churg-strauss
steroids
Microscopic polyangiitis is thought to be a group of inflammatory vascular lesions affecting small vessles that are in response to _____substances
exogenous like TB, aspirin, cillins,
Pathology of Microscopic polyangiitis
fibrinoid necrosis
Wegener Granulomatosis associated with which ANCA
c-ANCA (PR3-ANCA)
Churg-Strauss ANCA
p-ANCA, MPO-ANCA
Microscopic Polyangiitis ANCA
p-ANCA
Churg-Strauss common presentation
with asthma/allergy and eosinophilia
Buerger disease
smoking, autoamputation