apolipoproteins and transporters

Question 1

high LDL proteins implicated

Answer 1

apoB
apoE
LDL receptor

Question 2

low HDL proteins implicated

Answer 2

ApoA-1, ABCA1

Question 3

VLDL TAG or Chylomicron TAG

Answer 3

apoC-11
lipoprotein lipase (LPL)
LCAT

Question 4

protein specific to chylomicron

Answer 4

apoB-48

Question 5

deficiency in apoC-11 would give you what sort of lab numbers?

Answer 5

increased chylomicron

Question 6

severely low HDL numbers as well as severe atherosclerosis and xantomas seen in a kid could be?

Answer 6

Tangier disease implicating ABCA1 mutation

Question 7

apoE deficiency could lead to?

Answer 7

dysbetalipproteinemia

Question 8

possibilities if triacyglycerides are high

Answer 8

apoC-11 or LPL deficiency

Question 9

ABCA1 mutation or deficiency would lead to?

Answer 9

low HDL

Question 10

what are possibilities if LDL is high?

Answer 10

apoB (Decreases affinity to LDL) or LDL receptor deficiency

Question 11

high TAGs and high Chylomicrons could be a defect in?

Answer 11

apoC-11

Question 12

high cholesterol in plasma and high LDL cholesterol could be a deficiency in?

Answer 12

apoB-100