cardiomyopathies Flashcards
most common cardiomyopathy?
Dilated: left ventricular or biventricular dilation, impaired contractility and eventually CHF
Pathologic findings of dilated cardiomyopathy
Atrophy and fibrosis
Secondary dilated cardiomyopathies caused from?
Toxins: EtOH, cobalt, catecholamines, cyclophasmiades, cocaine
Pregnancy
Viral (cocksakie)
Cardiomyopathy that could come from genetic mutations mainly of the sarcomere (beta-myosin heavy chain or binding protein C)
Hypertrophic cardiomyopathy
young athlete falls dead?
Hypertrophic cardiomyopathy
treatment of hypertrophic cardiomyopathy?
beta blocker, Ca channel blocker, surgery
Cardiomyopathy that is associated with a group of diseases where myocardial or endocardial abnormalities limit diastolic dilling but allow the contractil fx to be pretty normal
restrictive cardiomyopathy
Least common cardiomyopatht
restrictive
Endomyocardical fibrosis (africa), Loefller endocarditis, or endocardical fibroelastosis (2 yo) associated with
restrictive cardiomyopathies
Pathological findings with restrictive cardiomyopathies
grayish/white thickened endocardium
mural thrombi
fibrotic endocardium
conditions with Myocardial involvement that can present with restrictive cardiomyopathies
amyloidosis
sarcoidosis
storage disease (Fabry, Pompe, Iron storage Hemochromatosis)
Arrhythmogenic cardiomyopathy pathologic findings
adipose/fibroadipose replaces the ventricular myocardium
myocarditis can come from
virus
immune related reactions
sarcoidosis