Restrictive lung disease

Question 1

Typical presentation of idiopathic pulmonary fibrosis?

Answer 1

• 55-75yo
• progressive Dyspnea, chronic dry cough
• physical exam: elevated RR, bibasilar rales
• subsequent hypoxemia, cyanosis. clubbing

Question 2

Gross characteristics of idiopathic pulmonary fibrosis?

Answer 2

cobblestoning of the pleural surface

Question 3

Typical gross appearance related to Usual interstitial pneumonia?

Answer 3

Honeycomb fibrosis of the lung indicative of end stage lung disease

Question 4

What king of granulomas specific to sarcoidosis?

Answer 4

non-caseating

Question 5

Sarcoidosis typical presentation?

Answer 5

African american woman with fatigue, aches and pains, blurry vision, SOB, dry eyes, cutaneous bumps, uveitis, enlarged liver

Question 6

Clinical findings of sarcoidosis?

Answer 6

abnormal X-Rays

Increased ACE

Increased 24hr Ca excretion

CD4/CD8 ratio> 5

Question 7

Pneumoconiosis is related to which occupational hazard?

Answer 7

inhaling mineral dust, organic particles, chem vapors

example: coal, asbestos, stone

Question 8

Anthracosis associated with Pneumoconiosis involved macrophages accumulating where?

Answer 8

along lymphatics or lymphoid tissue.

Question 9

Which interstitial lung disease is most associated with smoking?

Answer 9

Desquamative interstitial pneumonia

Question 10

What are some complications of restrictive lung diseases?

Answer 10

pulmonary htn

Honeycomb lung