Small Ruminants Flashcards
Which of the following organisms is known to be a blood sucker of the abomasum in sheep and goats?
- Fasciola gigantica
- Ostertagia ostertagii
- Strongyloides spp
- Haemonchus contortus
Answer: Haemonchus contortus
Explanation
The correct answer is Haemonchus contortus.
Ostertagia is not considered a blood sucker; instead this organism invades the abomasal wall.
Strongyloides spp are intestinal threadworms that migrate to the intestines by first penetrating the oral mucosa or the skin, entering the bloodstream, and then heading for the heart. Afterward, they travel to the lungs and trachea, where they are swallowed and enter the intestines. Fasciola gigantica is a liver fluke.
A farmer comes to you because many of his sheep are dying acutely. You perform a necropsy which shows dark blue, hemoglobin filled kidneys. This is most consistent with what condition of sheep?
- Iron deficiency
- Leptospirosis
- Urea toxicity
- Copper toxicity
Answer: Copper toxicity
Explanation
The correct answer is copper toxicity. Sheep are highly susceptible to copper toxicity. Because this causes an acute hemolytic crisis, the most common signs are acute death, icterus, depression, hemoglobinuria, increased respiratory rate, and weakness. Pathology often shows dark, hemoglobin filled kidneys (“gun metal blue”). Goats and cattle are less susceptible to copper toxicity.
***PowerLecture: Nutritional Management and Diseases
Several members of a recently shorn flock of sheep have developed abscesses in the mandibular, prescapular, parotid, and prefemoral lymph nodes. You lance an abscess and obtain some of the thick, white to greenish pus for culture. After growing on an agar plate for 48 hours you note that there are several small whitish-to-opaque colonies which can be easily pushed across the plate like a hockey puck. What is your diagnosis?
- Staphylococcus aureus
- Streptococcus ovis
- Corynebacterium pyogenes
- Corynebacterium pseudotuberculosis
Answer: Corynebacterium pseudotuberculosis
Explanation
Corynebacterium pseudotuberculosis causes caseous lymphadenitis in sheep and goats. The clinical signs and culture results are classic for C. pseudotuberculosis (especially the hockey puck feature).
***PowerPage: Top 10 Sheep and Goat Diseases
***PowerLecture: Caseous Lymphadenitis
Many young (<9 months) rams in a herd develop swelling and edema around the head and neck. There is a serohemorrhagic exudate and local tissue necrosis. What is the most likely cause?
- Clostridium novyi type A
- Corynebacterium pseudotuberculosis
- Mycobacterium bovis
- Clostridium chauvoei
Answer: Clostridium novyi type A
Explanation
The correct answer is Clostridium novyi type A. Cl novyi type B causes Black disease, a liver disorder, in sheep.
Type C is usually nonpathogenic. Type D is also called Cl hemolyticum and causes redwater (bacillary hemoglobinuria) in cattle and sheep.
This is a description of bighead, a disease in young rams where the clostridial organism, which is present in soil and feces, enters through wounds received from head butting and causes the signs described.
Treatment is generally debridement, disinfection, and penicillin.
***PowerPage: Clostridial Diseases
Infection of the pregnant ewe with what virus can result in lambs that have dark and hairy fleece around the head and shoulder that grow poorly and tremor?
- Bluetongue virus
- Akabane virus
- Cache Valley Virus
- Border disease virus
Answer: Border disease virus
Explanation
The correct answer is border disease virus. Ewes infected during gestation can have lambs that are aborted, macerated, or mummified but surviving ones may exhibit the “hairy shaker” syndrome described due to infection of hair follicles and the cerebellum. The other viruses listed can cause abortions but cause different signs in the lambs. Bluetongue can cause hydranencephaly. Akabane can cause dystocia and arthrogryposis.
Cache Valley virus can cause brachygnathia, hydranencephaly, microencephaly, and spinal cord hypoplasia.
***PowerPage: Border Disease
You are called to a goat dairy in Mississippi and asked to perform a postmortem on several 3- to 5-month old kids, which are pale. You note that the abomasum contains many Haemonchus contortus. Other animals of various ages appear anemic (pale, rapid HR, and weak). The owner has been treating all her goats with fenbendazole at two-month intervals for several years now. What is the explanation for this anemia likely to be?
- Hypobiotic larvae
- Resistant parasites
- Iron deficiency anemia
- Copper deficiency anemia
- Vitamin B12 deficiency
Answer: Resistant parasites
Explanation
Haemonchus is a blood sucker and causes anemia. Haemonchus, Ostertagia, and some other trichostrongyles can become resistant to anthelmintics. In addition, some anthelmintics are not as effective against hypobiotic larvae. You should recommend several management changes and use a new anthelmintic such as ivermectin.
**PowerPage: Caprine Intestinal Worms
**PowerLecture: Intestinal Worms
What is the cause of grass tetany in goats?
- Magnesium toxicity
- Calcium deficiency
- Copper deficiency
- Mycotoxins
- Magnesium deficiency
Answer: Magnesium deficiency
Explanation
The correct answer is magnesium deficiency. Magnesium is important for nervous system function and many enzymatic reactions. The skeletal reserves of magnesium are much smaller than the calcium reserve.
Magnesium deficiency leads to grass tetany. Magnesium toxicity is rare. Grass tetany usually occurs in lactating animals in the early spring on pastures that are well-fertilized with nitrogen and potassium, because high levels of these inhibit magnesium absorption from the Gl tract. Copper deficiency causes enzootic ataxia. If you chose mycotoxins, you were probably thinking of grass staggers, which is a different disease.
What species are primarily affected by both internal and external caseous lymphadenitis, a manifestation of Corynebacterium pseudotuberculosis?
- Goats and pigs
- Pigs and horses
- Cows and sheep
- Sheep and goats
- Horses and cows
Answer: Sheep and goats
Explanation
The cutaneous abscesses caused by this organism also affect cattle. Horses experience pectoral abscesses, internal abscesses, and other sites, as well ulcerative lymphangitis (also caused by C. pseudotuberculosis) of the limbs.
***PowerLecture: Caseous Lymphadenitis
Bluetongue will affect primarily which species with clinical signs of illness?
- Goats
- Cows
- Horses
- Sheep
- Pigs
Answer: Sheep
Explanation
The correct answer is sheep. Cattle may suffer reproductive losses, but they rarely show clinical signs of the systemic disease. Culicoides gnats vector bluetongue virus. Bluetongue is in the Reoviridae family. In sheep, the virus causes vasculitis and leakage of serum resulting in initial signs that include fever, edema of the face, muzzle, lips, and ears, and respiratory difficulty. Ptyalism and hyperemia will also be present. You can expect to see large amounts of mucopurulent nasal discharge. The tongue might be cyanotic (hence the name of the disease). Oral lesions will be present that will progress to ulcers and thus need to be differentiated from other ulcer producing diseases such as foot-and-mouth disease. Pulmonary edema and lameness are also often present. Bluetongue also causes teratogenic and reproductive effects both in sheep and cattle. If you see a picture of a stillborn or weak calf with “white eye calf syndrome” it is possibly a result of being infected with bluetongue. These calves have white eyes because they are born with congenital cataracts.
***PowerLecture: Blue Tongue
Which of the following disorders of goats can be controlled by genetic testing?
- Beta mannosidosis
- Penile papillomas
- Scrapie
- Corynebacterium pseudotuberculosis
Answer: Beta mannosidosis
Explanation
Beta mannosidosis is a disorder of Anglo-Nubian goats that causes fatal neurological symptoms in newborns and is an autosomal recessive mode of inheritance.
Scrapie is a prion-cused disorder. In sheep, scrapie can be controlled by genetic testing to eliminate the susceptible animals. To date that is not possible with goats. Corynebacterium pseudotuberculosis is a bacterial disease known as boils. Papillomas are viral.
What are the most common etiological agents of contagious footrot in sheep?
- Prevotella melaninogenicus and Fusobacterium necrophorum
- Dermatophilus congolensis and Fusobacterium necrophorum
- Trueperella pyogenes and Dichelobacter nodosus
- Dichelobacter nodosus and Fusobacterium necrophorum
Answer: Dichelobacter nodosus and Fusobacterium necrophorum
Explanation
Remember, these pathogens are highly contagious in sheep. As with cattle, the lesion will be in the interdigital space.
Trueperella pyogenes (formerly Arcanobacterium pyogenes) may cause footrot in cattle.
Prevotella melaninogenicus is one of the main causes of footrot in cattle, along with Fusobacterium necrophorum.
Dermatophilus congolensis is responsible for strawberry footrot in sheep. 10% zinc sulfate foot baths can be used to treat.
Lameness in sheep and goats due to infectious footrot is associated with wet conditions. What microorganism is considered essential for the disease to occur?
- Brucella ovis
- Corynebacterium pseudotuberculosis
- Campylobacter jejuni
- Dichelobacter nodosus
- Fusobacterium necrophorum
Answer: Dichelobacter nodosus
Explanation
Formerly called Bacteroides nodosus, this organism is the key to diagnosing infectious (contagious) footrot.
Fusobacterium necrophorum is also often present as a secondary invader in cases of footrot.
A male goat presents for vocalizing and straining to urinate. He has been kicking at his abdomen. You detect crystals adherent to the hairs around the prepuce (see image). What condition should you suspect and try to rule out first?
- Lower intestinal obstruction
- Urinary tract obstruction
- Acute severe pyelonephritis
- Upper intestinal obstruction
Answer: Urinary tract obstruction
Explanation
The correct answer is urinary tract obstruction due to calculi. This should be suspected in all male and castrated male goats (and sheep) with non-specific signs of disease or discomfort because it is so common. Common clinical signs associated with urinary tract obstruction are vocalization and dribbling of urine. Heaving or forceful abdominal contractions may be seen. Hematuria, dysuria, prolonged urination, and apparent abdominal pain are also common signs. The most important step of evaluation is exteriorization of the penis and examination of the urethral process because this is the most common site of blockage. In severe cases the entire urethra may be filled with calculi.
***PowerLecture: Urolithiasis In Ruminants
Several young sheep (3-4 months old) in a flock are showing signs of depression, head pressing, opisthotonos, diarrhea and blindness. As you investigate this problem, you realize that the farmer has been mistakenly feeding them horse feed. What disease do the sheep most likely have?
- Polioencephalomalacia
- Brain abscesses
- Hepatic encephalopathy
- Listeriosis
Answer: Polioencephalomalacia
Explanation
The correct answer is polioencephalomalacia (thiamine deficiency). This most commonly occurs in lambs being fed diets that are high in concentrates or molasses such as horse feed. This occurs because in normal lambs, ruminal bacteria produce sufficient thiamine to meet their requirements. Excess feeding of concentrates leads to ruminal acidosis, decreases the population of thiamine-producing bacteria, and increases production and activity of ruminal thiaminase. Other causes of polioencephalomalacia are bracken fern ingestion due to thiaminase in the plant, overdose of amprolium which is a thiamine analog, and high dietary sulfate.
Clinical signs include cortical blindness, head pressing, and incoordination progressing to recumbency, opisthotonos and convulsions. Treatment is with thiamine replacement. Diagnosis is usually based on clinical signs and necropsy findings, but blood thiamine levels and erythrocyte transketolase activity can be measured.
Classic necropsy lesions are a soft, edematous cerebral cortex with gray-yellow discoloration and flattened gyri.
***PowerPage: Top 10 Sheep and Goat Diseases
A farmer complains to you that many of his sheep have been doing poorly. You visit his flock and find many listless, emaciated adult sheep that are dyspneic and tachypneic. The sheep have normal temperatures, appetites, and no adventitious lung sounds. What is your top differential?
- Oestrus ovis infestation
- Ovine Progressive Pneumonia
- Pasteurella pneumonia
- Chlamydia psittaci pneumonia
Answer: Ovine Progressive Pneumonia
Explanation
Ovine Progressive Pneumonia is caused by a lentivirus, also known as Maedi-Visna virus. This generally causes a chronic, progressive condition, and affected sheep tend to be afebrile and maintain their appetites as long as they do not develop secondary bacterial pneumonia. This is in contrast to Pasteurella pneumonia, which tends to be much more acute. Clinical signs of Oestrus ovis tend to be more confined to the nares. Chlamydial pneumonia is rare in sheep.
Which of the following organisms is known to be a blood sucker of the abomasum in sheep and goats?
- Haemonchus contortus
- Strongyloides spp
- Fasciola gigantica
- Ostertagia ostertagii
Answer: Haemonchus contortus
Explanation
The correct answer is Haemonchus contortus. Ostertagia is not considered a blood sucker; instead this organism invades the abomasal wall. Strongyloides spp are intestinal threadworms that migrate to the intestines by first penetrating the oral mucosa or the skin, entering the bloodstream, and then heading for the heart. Afterward, they travel to the lungs and trachea, where they are swallowed and enter the intestines. Fasciola gigantica is a liver fluke.
An adult sheep presents with clinical signs of shaking its head, rubbing its nose, and stomping its feet. It has mucopurulent nasal discharge, stridor, and is sneezing. What insect is most likely responsible for this sheep’s signs?
- Simulium
- Culicoides
-Melophagus ovinus - Oestrus ovis
- Tabanus
Answer: Oestrus ovis
Explanation
The correct answer is Oestrus ovis. This fly deposits larvae in the nostrils of the sheep using its ovipositor. The larvae migrate up the nasal passage into the dorsal turbinates and sinuses where they develop for weeks before coming out. Excessive infestations result in clinical signs and may elicit a hypersensitivity reaction.
What is the most common cause of infectious abortion in sheep in North America?
- Leptospira
- Bluetongue virus
- Campylobacter
- Coxiella
- Brucella
Answer: Campylobacter
Explanation
Campylobacter infection (or vibriosis) is the most significant cause of abortion in sheep in North America. C. jejuni is the most common and C. fetus is the other main cause of abortion. Other common causes are Toxoplasma and Chlamydia psittaci. Bluetongue is much less common. Brucella ovis rarely causes abortion in sheep although it does cause epididymitis. Sheep are not very susceptible to abortion from leptospirosis. Q fever, or Coxiella burnetii, is an uncommon cause of abortion and is more of concern due to zoonotic potential.
A goat dairy is experiencing diarrhea 2 to 3 weeks after weaning at 6 weeks of age. You find numerous Eimeria oocysts in the feces. In addition to improving sanitation in the kid pens and decreasing exposure to Eimeria, which of the following can also be recommended?
- Feed coccidiostat preventative to kids starting at weaning
- Treat all kids at weaning with tetracyclines for 5 days
- Treat all kids for 5 days with Ivermectin at weaning
- Vaccinate against Eimeria caprina
Answer: Feed coccidiostat preventative to kids starting at weaning
Explanation
Amprolium and other preventive drugs can be effectively used to suppress clinical coccidiosis. There is no vaccine.
***PowerPage: Top 10 Sheep and Goat Diseases
A farmer complains to you that many of his sheep have been doing poorly. You visit his flock and find many listless, emaciated adult sheep that are dyspneic and tachypneic. The sheep have normal temperatures, appetites, and no adventitious lung sounds. What is your top differential?
- Ovine Progressive Pneumonia
- Chlamydia psittaci pneumonia
- Oestrus ovis infestation
- Pasteurella pneumonia
Answer: Ovine Progressive Pneumonia
Explanation
Ovine Progressive Pneumonia is caused by a lentivirus, also known as Maedi-Visna virus. This generally causes a chronic, progressive condition, and affected sheep tend to be afebrile and maintain their appetites as long as they do not develop secondary bacterial pneumonia.
This is in contrast to Pasteurella pneumonia, which tends to be much more acute. Clinical signs of Oestrus ovis tend to be more confined to the nares.
Chlamydial pneumonia is rare in sheep.
A 3-year old Nubian male goat presents with a history of breaking into a bag of grain meant for horses. What disease process are you concerned about?
- Rumen acidosis (grain overload)
- Acute hypocalcemia
- Rumen alkalosis
- Abomasal impaction
Answer: Rumen acidosis (grain overload)
Explanation
The correct answer is acute rumen acidosis. Excessive consumption of grain or other readily fermentable carbohydrate will lead to replication of Streptococcus bovis and other gram positive bacteria in the rumen at first, lowering the rumen pH precipitously to below 4.5 and causing an increase in lactic acid. Lactobacilli will subsequently multiply due to the favorable conditions created. The goat cannot metabolize the D-lactic acid made by bacteria (mammals can only process L -Lactic acid which they produce themselves), and a systemic lactic acidosis results. Clinical signs include rapid HR, depression, anorexia, fluid-filled rumen, scleral injection, staggering, diarrhea after 24 hours, and damage to rumen mucosa.
***PowerPage: Top 10 Sheep and Goat Diseases
Which of these routes are likely methods of transmission of Mycoplasma pneumonia in goats?
- Venereally and via insect vector
- Transmammary and aerosol
- Transplacental and fecal-oral
- Via blood transfusion and urine contamination
Answer: Transmammary and aerosol
Explanation
The correct answer is transmammary and aerosol. In goats, Mycoplasma pneumonia is caused by the Mycoplasma mycoides subspecies mycoides ( large colony type) and M. capricolum. The organism is transmitted orally to kids through contaminated milk or colostrum. In adults, it is thought to be transmitted through the external auditory meatus or direct inhalation. The incubation period is approximately 6-10 days but can be up to several weeks. Affected animals will typically show signs of respiratory disease (fibrinous pneumonia).
Several kid goats age 10 to 12 weeks on a large goat dairy have developed high fevers, swollen and painful joints, and respiratory signs including tachypnea and dyspnea. One has died, and a post mortem exam reveals fibrinopurulent polyarthritis and interstitial pneumonia. Which is the agent most likely to be the cause of this outbreak?
- Corynebacterium pseudotuberculosis
- Trueperella pyogenes (formerly Arcanobacterium pyogenes)
- Mycoplasma mycoides ssp. mycoides
- Pasteurella multocida
- Mannheimia hemolytica
Answer: Mycoplasma mycoides ssp. mycoides
Explanation
Mycoplasma mycoides subsp. mycoides of the large-colony (LC) type is responsible for major problems in the US goat population. It can also cause acute septicemia and CNS signs in kids. Carrier goats maintain the infection in a herd, where it is transmitted to kids through milk or colostrum.
A sheep presents to you with a history of rubbing its wool raw in areas along the lumbar regions. The sheep has had substantial weight loss in the past few months and has become quite fractious. What is the most likely diagnosis?
- Bacterial meningitis
- Listeria monocytogenes
- Rabies
- Scrapie
Answer: Scrapie
Explanation
The correct answer is scrapie. Scrapie is an afebrile neurologic disease of sheep that is a chronic, progressive, degenerative neurologic disease. It is one of the transmissible encephalopathies (like mad cow disease) caused by a prion. Clinical signs depend on the regions of the brain that are affected but usually include behavior changes including aggressiveness, failure to herd, unsteady gait, floppy ears, self-mutilation (pruritus), and in end stages, blindness, seizures, and an inability to swallow. Rabies is a differential for this sheep although clinical signs of rabies are usually more rapid in progression, with an ascending paralysis. However, aggression and any other neurologic signs can be seen with rabies. Bacterial meningitis in sheep is frequently associated with tail docking and presents as a progressive ascending paralysis. Neck pain is also frequently present. Clinical signs of listeriosis are usually loss of the ability to eat, dehydration, and often asymmetrical cranial nerve V or XII signs, including dropped jaw, loss of saliva, and dysphagia.
**PowerPage: Top 10 Sheep and Goat Diseases
**PowerLecture: Scrapie
Several ewes in a large flock, all of which are in late gestation, have not been able to rise to the standing position. They are being fed good quality grass and alfalfa hay. It is December and the weather is cold. They have reduced feed intake and the most severely affected individuals appear blind and depressed. The physical exam is otherwise not very revealing except that all have significant ketonuria. Which of the following disorders is the most likely and must be ruled out?
- Hypomagnesemia
- Amsinckia toxicity
- Liver flukes
- Pregnancy toxemia
- Type 2 ostertagiasis
Answer: Pregnancy toxemia
Explanation
Pregnancy toxemia is the result of multiple fetuses and insufficient energy intake in late gestation. Cold weather increases energy needs and often precipitates this disorder. Being overweight initially seems to make this disorder more likely. Affected ewes often have low calcium and potassium and high beta-hydroxybutyrate levels.
***PowerLecture: Reproductive Management
A sheep presents in a sitting position with apparently normal forelimbs and hyperreflexia of the hind limbs. Where would you localize the lesion to?
- Cerebrum
- C6-2 myelopathy
- L4-S3 myelopathy
- T3-L3 myelopathy
- Brainstem
Answer: T3-L3 myelopathy
Explanation
The correct answer is T3-L3 myelopathy. With a T3-L3 myelopathy, thoracic limbs would be normal because the nerve roots to the limbs emerge from the spinal cord cranial to the injury. Hyperreflexia to the pelvic limbs is an upper motor neuron sign indicating a lesion cranial to L4. A C6-2 myelopathy would cause lower motor neuron signs to the thoracic limbs. Cerebral and brainstem lesions would be unlikely to cause this type of lesion distribution.
A sheep presents to you for nasal discharge and face rubbing. You perform cytology on the copious discharge and note numerous eosinophils and mast cells. What is the most likely diagnosis?
- Actinomyces sinusitis
- Melophagus ovinus infestation
- Oestrus ovis infestation
- Enzootic nasal tumor
- Sheep diphtheria (Fusobacterium necrophorum)
Answer: Oestrus ovis infestation
Explanation
The correct answer is Oestrus ovis infestation. Adult flies deposit larvae around the animals’ nostrils; the larvae then migrate up the nasal passages into the turbinates and sinuses. With time and multiplication of the larvae, hypersensitivity develops with the marked clinical signs of nasal discharge and face rubbing and shaking.
Secondary bacterial infection can occur. The discharge usually contains numerous eosinophils and mast cells, which confirms the diagnosis in this case. Further confirmation could be achieved with radiographs showing mineralized bots or with endoscopy, but this is not usually necessary.
Enzootic nasal tumor could have similar clinical signs but tends to cause more dyspnea and would not have the eosinophils and mast cells seen in the discharge.
Fusobacterium causes necrotic laryngitis in sheep when there is perforation to the mucous membranes. Clinical signs are more of coughing and dyspnea; there would not be nasal discharge.
Actinomyces pyogenes infection is also unlikely to cause nasal discharge and if it did, you would not observe eosinophils and mast cells in the discharge.
Treatment of Oestrus ovis is with ivermectin.
You examine a herd of sheep and find that many sheep have proliferative, crusting lesions of the mucocutaneous junctions of the mouth and nose. They are otherwise relatively healthy, although some of the nursing females have similar lesions on their udders. The farmer reports that many of his sheep have had these before and that it eventually just goes away. What is the most likely diagnosis?
- Vesicular stomatitis
- Foot-and-mouth disease
- Bluetongue
- Contagious ecthyma
Answer: Contagious ecthyma
Explanation
The correct answer is contagious ecthyma. FMD, VSV, and bluetongue cause vesicles and ulcers rather than proliferative, crusting lesions and usually will have other systemic signs as well; also, they are unlikely to recover spontaneously. Contagious ecthyma is a zoonotic poxvirus.
What is the most common site of obstruction in male goats with urolithiasis?
- External urethral sphincter
- Urethral process
- Trigone
- Internal urethral sphincter
Answer: Urethral process
Explanation
The correct answer is the urethral process. The most common sites of obstruction in male goats are the urethral process and the distal sigmoid flexure. This is because these regions are narrower intraluminally and are physically predisposed to getting calculi stuck. Other sites including the trigone, ureter, and renal pelvis can obstruct from stones but are less common sites. Even when this obstruction is removed, re-obstruction commonly occurs as more stones leave the bladder.
***PowerLecture: Urolithiasis In Ruminants