Small Intestine Structure and Function Flashcards
What are the functions of the Duodenum?
Gastric acid neutralisation, digestion and iron absorption
What is the function of the Jejunum?
Nutrient absorption
What is the function of the Ileum?
NaCl/H2O absorption and chime deydration
What is the function of the villus cell?
They absorb nutrients
What is the function of the crypt cell?
They secrete Cl and water
How much water does the small intestine secrete per day?
Approx. 1.5l per day
How is water secreted in the small intestine?
Passively (osmotically) as a consequence of active secretion of chloride into intestinal lumen
What are the functions of water in the small intestine?
Maintaining luminal contents in liquid state
Promotes mixing of nutrients with digestive enzymes
Aids nutrients with digesting enzymes
Dilute and washes away potentially injurious substances
What are the two types of intestinal movement?
Segmentation and peristalsis
What is the function of segmentation in the small intestine?
Moves the chyme up and down which mixes the contents with digestive enzymes
What generates segmentation?
Depolarisation generated by pacemaker cell in the longitudinal muscle layer (Intestinal basic electrical rhythm produces oscillations in the membrane potential)
What is the migrating motility complex?
A pattern of peristaltic activity travelling down the small intestine
What are the functions of the MMC?
To move undigested material into the large intestine and limits bacterial colonisation of the small intestine
What hormone is involved in the initiation of MMC?
Motilin
What is the law of the intestine?
If the intestinal smooth muscle is distended:
Muscle on oral side of the bolus contracts
Muscle on anal side of bolus relaxes
Bolus is moved into area of relaxation towards colon