Small Intestine Structure and Function Flashcards
What functions does the pancreas have?
Endocrine and exocrine
The exocrine pancreas is responsible for
the digestive function of the pancreas
The exocrine pancreas secretes from
Acini -> ducts -> pancreatic sucts
glands via ducts, rather than directly into the blood
Pancreatic duct cells secrete bicarbonate which
What does this allow?
neutralises gastric acid and gastric contents
allows pancreatic enzymes to work
The acinar cells secrete
digestive enzymes
Acing cells contain digestive enzymes stored as
inactive zymogen granules
What does the storing of enzymes as their zymogen granules prevent?
Autodigestion of the pancreas
Enterokinase is bound to
the brush border of the duodenal enterocytes
What is the function of enterokinase?
Converts trypsinogen to trypsin
What does trypsin do?
Converts all other zymogens to their active forms
What are the different categories of pancreatic enzymes?
Proteases Nucleases Elastases Phospholipases Lipases Alpha-amylase
What is the function of proteases?
Cleave peptide bonds
What is the function of phospholipases?
Convert phospholipids to fatty acids
What is the function of lipases?
Convert triglycerides to fatty acids and glycerol
What group of pancreatic enzymes are responsible for hydrolysing DNA and RNA?
Nucleases
What group of pancreatic enzymes are responsible for converting starch to maltose and glucose?
Alpha-amylases
What group of pancreatic enzymes is responsible for collagen digestion?
Elastases
The endocrine functions of the pancreas involve the
secretion of various substances into the blood
Bicarbonate secretion is stimulated by
secretin
Zymogen secretion is stimulated by
cholecystokinin
Bicarbonate secretion is stimulated in response to
acid in the duodenum
Zymogen secretion is stimulated in response to
fat/amino acids in the duodenum
The pancreas is under neural control from vagal and local reflexes which are triggered by
arrival of organic nutrients in the duodenum
What are the three parts of the small intestine?
Duodenum
Jejunum
Ileum