Small Bowel Disease

Question 1

What tumours can be found in small bowel, where are they commonly found?

Answer 1

1. Adenocarcinoma - dudodenum and jejunum
2. Lymphoma - ileum
3. Carcinoid tumours - appendix and terminal ileum

• secondary tumours are much more common

Question 2

How to manage small bowel cancer?

Answer 2

Same as gastric cancer

• Surgery
• Chemo
• Radio

Question 3

What makes carcinoid tumours different from other tumour types?

Answer 3

Secrete hormones - in paticular serotonin

Question 4

Carcinoid syndrome occurs when and what is it?

Answer 4

Increased serotonin production (weird set of symptoms- along with red flag cancer symtpoms)
ADD

Question 5

Investigations of small bowel tumours?

Answer 5

Serum chromogranin A
24hrs urine secretion of 5-hydroxyinodoleactic acid
ADD

Question 6

management of small bowel tumours

Answer 6

Surgical resection

Octreotide (somatostatin analogue - reduces serotonin levels) - relieve symptoms