Small Bowel Flashcards
Primary site of chemical digestion
duodenum
Main site of nutrient absorption
jejunum
SIBO treatment
rifaximin 550 mg TID for 14 days
SIBO diagnosis
positive lactulose breath test (or glucose)
Lactose intolerance diagnosis
positive hydrogen breath test
Lab positive in celiac
tTG IgA
Celiac diagnostic step
small bowel biopsy
Depth of inflammation for Crohn’s
transmural
Tropical sprue treatment
250 mg tetracycline QID for 2-3 months, then TID up to 6 months
B12 level that is diagnostic for B12 deficiency
< 150
MMA and homocysteine in B12 deficiency
elevated, elevated
MMA and homocysteine in folate deficiency
normal, elevated
Whipple disease diagnosis (2)
PAS-positive macrophages in tissue biopsy
PCR for Tropheryma whipplei
Whipple disease treatment
1) ceftriaxone (or penicillin)
2) then TMP-SMX for 1-2 years
Jejunal aspirate CFU in SIBO
> 105 CFU
Lab to differentiate folate and B12 deficiency
MMA (elevated w/ B12, normal w/ folate)
Part of small bowel where most nutrient absorption occurs
jejunum
Duodenum function/allows passage of (3)
digestion
pancreatic enzymes
bile
Jejunum function
nutrient absorption
rich blood supply
Ileum function/absorption (2)
bile salts
B12
Diagnostic serology for Celiac (2)
anti-tTG
anti-endomysial
Duodenal biopsy findings in Celiac (3)
villous atrophy
crypt hyperplasia
increased intraepithelial lymphocytes
Causes of malabsorption (4)
Celiac
lactose intolerance
tropical sprue
pancreatic insufficiency
Diagnosis of malabsorption (3)
fecal fat
biopsy
serology
