Large Bowel Flashcards

1
Q

Microscopic colitis biopsy findings

A

lymphocytic or collagenous colitis

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2
Q

Layers of the bowel impacted by UC (2)

A

mucosa
submucosa

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3
Q

Chemo for colorectal cancer

A

FOLFOX

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4
Q

Components of FOLFOX (3)

A

5-fluorouracil
leucovorin
oxaliplatin

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5
Q

Antibiotics for uncomplicated diverticulitis (2)

A

ciprofloxacin + metronidazole

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6
Q

IBS-C fiber recommendations

A

increase intake

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7
Q

IBS-D fiber recommendations

A

decreased intake

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8
Q

Rome IV IBS criteria

A

1) symptoms lasting at least 6 months
2) occurring at least 1 day/week
3) for the past 3 months

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9
Q

Chronic diarrhea duration

A

> 4 wks

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10
Q

Serum ferritin indicative of anemia in chronic disease

A

> 100

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11
Q

Number of recurrences to consider FMT

A

2-3

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12
Q

Success rate of FMT

A

> 90%

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13
Q

Polyp size to use snare polypectomy

A

< 1 cm

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14
Q

Components for Mayo score (4)

A

stool frequency
rectal bleeding
endoscopic findings
physician global assessment

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15
Q

Mayo score

A

Stool Frequency:
0: Normal
1: 1-2 stools more than normal
2: 3-4 stools more than normal
3: ≥5 stools more than normal

Rectal Bleeding:
0: None
1: Streaks of blood in stool
2: Obvious blood in stool
3: Passing blood alone

Endoscopic Findings:
0: Normal or inactive disease
1: Mild disease (erythema, decreased vascular pattern, mild friability)
2: Moderate disease (marked erythema, lack of vascular pattern, friability)
3: Severe disease (spontaneous bleeding, large ulcers)

Physician’s Global Assessment:
0: Normal
1: Mild disease
2: Moderate disease
3: Severe disease

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16
Q

Polyp size that EMR is indicated

A

> /= 2 cm

17
Q

Diagnosis of toxic megacolon

A

colonic dilation > 6 cm on x-ray w/ systemic toxicity

18
Q

Toxic megacolon treatment

A

IV steroids
cipro + flagyl
surgery if no improvement in 24-48 hours

19
Q

UC vs Crohn’s histology

A

UC - crypt abscesses, mucosal inflammation
Crohn’s - noncaseating granulomas, transmural inflammation

20
Q

FAP surgical management

A

colectomy by age 25 if multiple polyps

21
Q

Genetic testing for Lynch Syndrome (3)

A

MLH1
MSH2
MSH6

22
Q

Peutz-Jeghers genetic mutation

A

STK11 gene

23
Q

TNF inhibitor indicated for FISTULIZING Crohn’s

A

infliximab (remicade)

24
Q

FAP inheritance pattern

A

autosomal dominant

25
Q

Peutz-Jeghers inheritance pattern

A

autosomal dominant

26
Q

FAP genetic mutation

A

APC

27
Q

Test for chronic inflammation

A

ESR

28
Q

Test for acute inflammation

A

CRP