Pancreas

Question 1

Part of pancreas that secretes digestive enzymes and bicarbonate

Answer 1

head

Question 2

Part of pancreas that secretes insulin and glucagon

Answer 2

body

Question 3

Part of pancreas that produces digestive enzymes and insulin

Answer 3

tail

Question 4

Fecal elastase in chronic pancreatitis

Answer 4

<200

Question 5

Pancrelipase (Creon) dose (pancreatic insufficiency, chronic pancreatitis)

Answer 5

10,000 - 25,000 lipase units/meal

Question 6

Cells that make up the exocrine pancreas

Answer 6

acinar cells

Question 7

Cells that make up the endocrine pancreas

Answer 7

islets of Langerhans

Question 8

Hormones secreted by the islets of Langerhans (3)

Answer 8

insulin, glucagon, somatostatin

Question 9

Gene testing for suspected hereditary pancreatitis (2)

Answer 9

CFTR gene (cystic fibrosis)
PRSS1 (hereditary pancreatitis)

Question 10

Most common cause of hereditary pancreatitis

Answer 10

PRSS1 gene mutation

Question 11

PRSS1 mutation inheritance pattern

Answer 11

autosomal dominant

Question 12

Chemo options for pancreatic cancer (2)

Answer 12

FOLFIRINOX
gemcitabine

Question 13

Lipase level diagnostic for pancreatitis (factor of ULN and rough number)

Answer 13

3x ULN, ~400 (ULN is around 140)

Question 14

Stool elastase diagnostic for pancreatic insufficiency

Answer 14

< 200 ug/g

Question 15

Early fluid resuscitation amount for pancreatitis

Answer 15

20-30 mL/kg

Question 16

Ranson’s criteria (initial) (5)

Answer 16

age > 55
WBC > 16,000
BG > 200
LDH > 350
AST > 250

Question 17

Indications for drainage of a pancreatic pseudocyst (3)

Answer 17

1) > 6 cm
2) symptomatic
3) or infected

Question 18

Preferred fluid and rate for acute pancreatitis treatment

Answer 18

LR @ 250-500/hr

Question 19

Fecal elastase indicative of exocrine insufficiency

Answer 19

< 200

Question 20

Most common portion involved w/ pancreatic cancer

Answer 20

head

Question 21

Most common portion involved w/ pancreatitis

Answer 21

head

Question 22

Medication that reduces pancreatic secretions

Answer 22

octreotide