Small and large intestines part2 Flashcards

1
Q

terminal ileum infections ddx?

A

yersinia
amoebic colitis
TB

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2
Q

normal colon microscopy looks like?

A

nice rack of test tubes: unlike architectural disarray in Crohn’s from chronicity

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3
Q

features of terminal ileum biopsies?

A

granulomas

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4
Q

features of a chronically inflamed terminal ileum?

A

thickened wall
narrowed lumen
evidence of perforation
linear ulcers: cobblestone muscosa

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5
Q

endoscopy will only get to what layer in GI?

A

only the mucosal layer

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6
Q

complications of Crohn’s?

A
strictures
perforations
fistulas
abcesses
B12 deficiency
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7
Q

extraintestinal manifestations of Crohn’s?

A

uveitis
erythema nodosum
primary sclerosing cholangitis

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8
Q

classic extra-lung manifestation of TB?

A

terminal ileum

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9
Q

big complication of ulcerative colitis?

A

toxic megacolon

distension so great: self-infarction, perforation

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10
Q

course of UC?

A

curative or intermittent exacerbation

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11
Q

complications of UC?

A

PSC
not really perforation or fistulas because no knife-like ulcers
-dysplasia

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12
Q

what influences risk of cancer development in UC?

A

duration
activity of disease
extent (pan-colitis)

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13
Q

aetiology of UC?

A

idiopathic

possibly due to barrier breakdown

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14
Q

right side of bowel cancer?

A

iron deficiency anaemia
fatigue
metastasis

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15
Q

left sided bowel cancer?

A

bright red

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16
Q

why resect big segment of bowel in cancer?

A

to get the whole lymph node field

17
Q

predisposing factors for colon cancer

A

family history (FAdenomatousPolyposis)
obesity
smoking
lynch syndrome (young Age)

18
Q

metastases of colon cancer

A

peritoneum

liver

19
Q

metastases of rectal cancer?

A

lungs

some liver

20
Q

lynch syndrome inheritance?

A

autosomal dominant