Lung Pathology 2 Flashcards

1
Q

miliary TB likes to go where?

A

boen marrow, spleen kidneys other LNs

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2
Q

tuberculosis bronchopneumonia is?

A

affects entire lung, happens in immunosuppressesed

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3
Q

secondary TB is what?

A

reactivation in dormant focus

reinfection in immunosuppressed

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4
Q

where is secondary and post-primary Tb occue in lung usually?

A

apex of upper lobe

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5
Q

what kind of necrosis in TB?

A

casseus

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6
Q

granulomas contain what 3 things

A

Langhans’ giant cells, lymphocytes, epithelioids

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7
Q

Ziehl-Neilson Stain for what?

A

TB

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8
Q

other granulomatous infections?

A

fungi
mycobacteria
parasites
sarcoid, lymphoma, TB

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9
Q

Sarcoidosis causes what kind of lung disease?

A

bilateral interstitial lung disease

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10
Q

what blood test for Sarcoidosis show?

A

raised ACE in 75% of pt

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11
Q

Sarcoidosis diagnosis of?

A

exclusion

exclude TB and malignancy

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12
Q

causes of bilateral hilar enlargement

A
Sarcoidosis
lymphoma
TB
matastatic carcinoma
fungal/viral
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13
Q

who normally gets Sarcoidosis?

A

age 20-40

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14
Q

who normally gets interstitial pneumonia?

A

more elderly >70

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15
Q

what is honeycomb lung?

A

irreversible end-stage manifestation of interstitial inflammaatory lung diseases

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16
Q

causes of honeycombing lung

A
miliary TB
asbestosis
Sarcoidosis
radiation
idiopathic interstitial lung disease
17
Q

pleural diseases divded into?

A

infective

non-infective

18
Q

most common infective causes of pleural diseases?

A

bacteria and TB

19
Q

common causes of non-infective pleural diseases

A

trauma
infarction
tumour

20
Q

exudate cause in lung?

A

damage to capillaries

21
Q

whats worse? exudate or transudate?

A

exudate, may indicate more damage

22
Q

chylous effusion contains?

A

lymphocytes

23
Q

mesothelioma contains lots of?

A

hylaronic acid

24
Q

cause of mesothelioma?

A

asbestos

25
Q

which asbestos fibres more dangerous?

A

thin and long fibres

26
Q

differential for mesothelioma?

A

lung cancer

overlap with adenocarcinoma

27
Q

average survival for mesothelioma?

A

12-15 months

28
Q

usual interstitial pneumonia aka?

A

idiopathic pulmonary fibrosis