Lung Pathology 2 Flashcards
miliary TB likes to go where?
boen marrow, spleen kidneys other LNs
tuberculosis bronchopneumonia is?
affects entire lung, happens in immunosuppressesed
secondary TB is what?
reactivation in dormant focus
reinfection in immunosuppressed
where is secondary and post-primary Tb occue in lung usually?
apex of upper lobe
what kind of necrosis in TB?
casseus
granulomas contain what 3 things
Langhans’ giant cells, lymphocytes, epithelioids
Ziehl-Neilson Stain for what?
TB
other granulomatous infections?
fungi
mycobacteria
parasites
sarcoid, lymphoma, TB
Sarcoidosis causes what kind of lung disease?
bilateral interstitial lung disease
what blood test for Sarcoidosis show?
raised ACE in 75% of pt
Sarcoidosis diagnosis of?
exclusion
exclude TB and malignancy
causes of bilateral hilar enlargement
Sarcoidosis lymphoma TB matastatic carcinoma fungal/viral
who normally gets Sarcoidosis?
age 20-40
who normally gets interstitial pneumonia?
more elderly >70
what is honeycomb lung?
irreversible end-stage manifestation of interstitial inflammaatory lung diseases
causes of honeycombing lung
miliary TB asbestosis Sarcoidosis radiation idiopathic interstitial lung disease
pleural diseases divded into?
infective
non-infective
most common infective causes of pleural diseases?
bacteria and TB
common causes of non-infective pleural diseases
trauma
infarction
tumour
exudate cause in lung?
damage to capillaries
whats worse? exudate or transudate?
exudate, may indicate more damage
chylous effusion contains?
lymphocytes
mesothelioma contains lots of?
hylaronic acid
cause of mesothelioma?
asbestos
