SM 2

Question 1

erythematous edematous papules and plaques +/- blisters/ ulcerate; presents w/ fever and malaise; associated w/ hematologic malignancies (AML), IBD, autoimmune disease (lupus); TX: prednisone

Answer 1

Sweet syndrome (aka acute febrile neutrophilic dermatosis)

Question 2

Ulcer w/ necrotic border that is pruple/ grayish and prulent center; Up neutrophilis but - culture; associated w/ IBD (UC or CD) and hematologic malignancies (AML); TX: prednisone 1st

Answer 2

Pyoderma gorgrenasum

Question 3

Tender erythematous subcutaneous nodules on lower legs (anterior); associated w/ many systemic diseases- TB, URI, CD, gastroenteritis, Sarcoidosis, Neds

Answer 3

Erythema Nodosum

Question 4

Pink to yellow-brown waxy papules or plaques on the face; enlarged tongue, swollen hands; pinch purpura (purpura on eyelids) and purpura on hands, abdomen; amyloid deposits cause fragile blood vessels

Answer 4

Amyloidosis

Question 5

Palpable multiple purpuras on lower legs/feet; caused by inflammation around capillaries by immune complex deposits; involve joint pain 30% of cases

Answer 5

Leukocytoclastic vasculitis

Question 6

hyperpigmented velvety plaques around neck and armpit; commonly caused by PCOS and insulin resistance/ diabetes; more common in dark individuals

Answer 6

acanthosis nigricans

Question 7

Red-brown to violaceus papules and plaques on face, neck, back, and tattoos; a systematic granulomatous disorder that commonly affects lungs, then heart; any organ system can be involved; granulomas on histology; death caused by a cardiac disease about 25% of cases

Answer 7

Sarcoidosis