Slides Flashcards
Pathologic (simple) fatty infiltration:
- centerolobulary
- pink spots are Granulocytes= inflammatory cells
Pathologic simple fatty liver infiltration
-see the pink Granulocytes and the fatdroplet or vacoules
Pathologic necrobiotic fatty infiltration:
- more fat droplets than hepatocytes in the parenchyma
- vacuoles increases in size = push the nucleus to side
- Nucleus–> necrobiotic degeneration( Karyopyknosis, Karyorrhexis, Karyolysis)
Zenker muscle necrosis (skeletal muscle)
-contractile substances of myofibrils necrotizes
*Discoid degeneration= necrotic area disintegrated into smaller or longer parts( marcrophages appear to remove degenerated proteins)
*Arrow= Giant cells/ multi-nucleated myocytes, sarcoplasm re-build the muscle fibers
Chronic demarcation:
- hyperaemic pulp( contain RBC) + haematoma
- Angiofibroblasts(innermost layer)
- Scar tissue( collagen fibers)
*chronic demarcation= CT encapsulates the haematoma, the tissue bw are called “granulation tissue”
- Granulation tissue= lymphocytes + plasma cells
- Fibroblasts cells differentiate into Fibrocytes
Chronic demarcation:
- Angiofibroblast tissue
- Necrosis
*hyperaemia, RBC
*Granulation tissue-> lymphocytes, plasmacell
*Fibrin
Tuberculum: LUNG tissue
-Granuloma formation w/ coagulation necrosis, central haemolytic area
*Mycobacterium tuberculosis or bovis
- Macrophages/ Histocytes (epitheloid cells= activated macrophages)
- Langhans type Giant cells inside granuloma
- Neutrophils= bacteria
- Calcification
*Miliary= many tubercles+ proliferative has many inflam cells
Phlegmone: Diffuse purulent inflammation
- see the that the tissue is from sub.cutan(due to fat)
- connective tissue loosened and pushed away from each other
*Pyogenic bacteria( Stap,Strept, Aracano, Proteus)
- You see a lot of NEUTROPHILS(purulent exudate)
- Edema and fluid filled dilated vessels( due to Haemostasis + hyperaemic tissue)
*Mononuclear cells= histocytes, plasma cells, lymphocytes
