Liver, muscle, Demarcation, Tuberculum Flashcards
1
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Pathologic simple fatty infiltration:
- fat droplets or vacoules in the cytoplasm of hepatocytes
- liver structure is maintained
- nuclei of hepatocytes are intact
- Granulocytes among the fat droplets
*Hypoxia due to anemia
2
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Pathologic necrobiotic fatty infiltration:
- vacuoles increase in size and push nucleus to the sides of the cell
- liver cells are enlarged w/ fat droplets in their cytoplasm (more fat/adipose than hepatocytes in parenchyma).
- Nuclei is undergoing breakdown process= necrobioti degeneration
*Karyopyknosis, Karyorrhexis, Karyolysis= irreversible
-recognizable structure of liver
3
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Pathologic simple fatty infiltration:
-start centero-lobulary
4
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Pathologic simple fatty infiltration:
-fat accumulation is in the cytoplasm in liver cells, and they are uniform and microvesicular
5
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Zenker muscle necrosis:
-normal vs necroticing muscle fiber (myofibrils)
6
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Zenker muscle necrosis:
- Macrophages(histocytes) appear to remove degenerated proteins
- Multinucleated myocytes (GIANT CELLS/BUD)= sarcoplasm rebuilding the muscle fibers and indicate sign of regeneration.
*Discoid degeneration= necrotic are disintegrated into smaller or larger parts
7
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Chronic demarcation:
- blood vessle in the middle with hemorrhages all around and orange color is the angiofibroblast area of demarcation
- hyperaemia (pulp) RBC
- Granulation tissue (lymphocytes, plasma cells)
- Fibrin
- Hematoma= localized collection of blood outside the blood vessel
8
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Chronic demarcation:
- blood vessle in the middle with hemorrhages all around and orange color is the angiofibroblast area of demarcation
- hyperaemia (pulp) RBC
- Granulation tissue (lymphocytes, plasma cells)
- Fibrin
- Hematoma= localized collection of blood outside the blood vessel
9
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Chronic demarcation:
- blood vessle in the middle with hemorrhages all around and orange color is the angiofibroblast area of demarcation
- hyperaemia (pulp) RBC
- Granulation tissue (lymphocytes, plasma cells)
- Fibrin
- Hematoma= localized collection of blood outside the blood vessel
10
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Tuberculum:
- Miliary tuberculosis in the lung (poppy seed like)
- microbronchus( poppy seed like)
- Granuloma (onion like)
11
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Tuberculum:
- Miliary tuberculosis in the lung (poppy seed like)
- microbronchus( poppy seed like)
- Granuloma (onion like)
12
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Tuberculum:
- Miliary tuberculosis in the lung (poppy seed like)
- microbronchus( poppy seed like)
- Granuloma (onion like)