Inflammation, tumors

Question 1

Answer 1

Phlegmone (Diffuse purulent inflammation):

=acute inflammation of soft tissue

• diffuse and no capsule
• purulent exudate= inflammatory cells( neutrophils ocean)
• edema and fluid filled dilated vessels due to hemostasis and hyperaemic tissue
• Microvascularthrombosis (DIC)
• collagen fibers
• Mononuclear cells identified( histocytes, plasma cells, lymphocytes)
• Histocytes w/ big vesucyar hyperchromatic nuclei
• Plasma cells (smaller then histocytes)

Question 2

Answer 2

Phlegmone( Diffuse purulent inflammation)

Question 3

Answer 3

Phlegmone (Diffuse purulent inflammation)

• microvascular thrombus
• SC adipocytes
• dilated filled blood vessel
• Loose CT wit wavy collagen fibers

Question 4

Answer 4

Phlegmone:

-segmented nuclei( granulocytes/neutrophils–> see nuclei segments= inflammation

Question 5

Answer 5

Hemorrhagic inflammation (Small intestines)

• can clearly see on the slide that it is a cross section from intestines
• External smooth muscle layer
• submucosa
• proprial layer w/mucosal membrane (enterocytes), Villi + a lot of extravasated RBC

*Parvovirus, E.coli, Salmonella, dietical problems, stress, trauma, Shock.

Question 6

Answer 6

Hemorrhagic inflammation:

• inflammatory cells present in the submucosa.
• the wite “bubles” = dilated blood vessels

Question 7

Answer 7

Fibrinous (Kroupous) inflammation:

-see clearly the fibrin strands/part in the lumen of the intestine/stomach

Question 8

Answer 8

Fibrinous (Kroupous) inflammation:

*muscle layers: inn–>out

1) mucosal layer
2) muscularis mucosa
3) submucosa
4) muscularis externa

Question 9

Answer 9

Malignant lymphoma:

• slide is dark purple, is a stomach look like a stomach
• see mass of neoplastic lymphocytes
• see mucous membrane

Answer 10

Malignant lymphoma(stomach)

• see the lymphocytic mass, cell proliferation with necrotized surface
• also remnants of propria glands
• no benign type of this tumor

Question 11

Answer 11

Malignant lymphoma:

• apoptotic cells
• mitotic figures
• lymphocytes

Question 12

Answer 12

Benign mixed tumor(mammary gland):

• chondroma
• osteoma

Question 13

Answer 13

Benings mixed tumor (mammary gl).

-myoepithelioma= spindle shaped cells, elongated myoepithelial cells with pale blue matrix around

Question 14

What is in the white part of the slide(round white part)

Answer 14

Benings mixed tumor (mammary gl).

-myoepithelioma= spindle shaped cells, elongated myoepithelial cells with pale blue matrix around

Question 15

Answer 15

Benings mixed tumor (mammary gl).

• ademona
• chondroma

Question 16

Answer 16

Mast cell tumor= mastocytoma:

-cytoplasmic granules/basophil “fired egg”= round cell, sometimes polygonal, central round nucleus

Question 17

Answer 17

Mast cell tumor= mastocytoma:

-cytoplasmic granules/basophil “fired egg”= round cell, sometimes polygonal, central round nucleus

Question 18

Answer 18

Melanoma malignum:

• melanin pigments
• melanocytic hyperplasia (lentigo)
• metastasis

Question 19

Answer 19

Melanoma malignum:

• no pigments in the granules in the collagen fibrous stroma
• cellular polymorphism

Question 20

Answer 20

Benign Trichoblastoma:

-see that the tissue is skin tissue

Question 21

Answer 21

Benign trichoblastoma:

• meduzoid pattern of stroma = multipotent germinative cells
• solid islands
• follicles