Sleep Flashcards
What is the wave frequency of alpha activity?
8-12 mhz
What is measured in sleep studies?
EEG [brain] EMG [muscle - chin] EOG [eyes] skin [conducting electricity] heartrate
What is wave frequency of Beta activity?
13-30 mhz
What is wave frequency of Theta sleep?
4-11.5 mhz
What is wave frequency of Delta sleep?
0-3 mhz
What is slow wave sleep?
delta - 0-3 mhz
What is the down state?
period of inhibition during slow oscillation in slow-wave sleep; neurons in neocortex are silent and resting
What is up-state in sleep?
Period of excitation during slow oscillation in slow wave sleep; neurons in neocortex briefly fire at high rate
What is indicated by lower frequency activity in brain?
Neurons are synchronising more
What do sleep spindles do?
Appear 2-5 times / minute in stages 1-4
consolidating memories,
correlation between sleep spindles and intelligence
What are K complexes?
Found only in stage 2 sleep
1/minute, triggered [not only] by loud noises
forerunners of delta activity
What is stage 3 sleep?
Contains 20-50 % delta activity
What is stage 4 sleep?
Contains >50% delta activity
What is slow wave sleep?
Stages 3-4
delta activity
What is most important part of slow wave sleep?
slow oscillations - <1Hz
consisting down state [neurons resting] and up state [period of excitation where neurons fire at high rate]
What happens approx 90 minutes into sleep cycle?
Neurons desynchronise; sprinkling of theta [stage 1] waves
eye movement
profound loss of muscle tone [EMG silent]
What happens when someone is aroused from REM sleep?
Alert and awake
Describe arousal from REM sleep?
Will respond to meaningful stimulation - eg name; awake and alert
What do people who are aroused from slow wave sleep report?
presence of thought, image, emotion
How many periods of REM sleep are in 8 hour block?
4-5
When do blocks of slow wave sleep happen?
Early in night [normally 2x stage 4, 4x stage 3]
What happens to brain in REM sleep?
cerbral blood flow and oxygen consumption are accelerated
increased activity
What happens to body in REM sleep?
Spinal and cranial motor neurons inhibited
Body paralysed
What happens to length of REM sleep periods over course of sleep?
Get longer
What are principle characteristics of Slow wave sleep?
EEG synchrony [slow waves]
Moderate muscle tonus
Slow or absent eye movements
Lack of genital activity
What are principle characteristics of REM sleep?
EEG desynchrony [rapid, irregular waves] Lack of muscle tonus REM Penile erection or vaginal secretion Dreams
During REM sleep, what happens to blood flow?
High in visual association cortex
Low in primary visual cortex and prefrontal cortex
What does high rate of blood flow in visual association cortex indicate?
visual hallucinations - dreams
What does low blood flow to prefrontal cortex in REM sleep create?
Confabulation, distortion of reality in dreams
Lack of time / organisation in dreams
What do REM sleep eye movements relate to?
Visual imagery in our dreams
What happens to other brain mechanisms [eg motor mechanisms] when we dream?
Become active if they are active in dream [eg increased blood flow to cortical and subcortical motor mechanisms]
What happens if a dream involves talking or listening?
Those parts of brain become active
What mental activity can accompany slow wave sleep/
Nightmares
How many people are affected by insomnia?
Approx 25% occasionally, 9% regularly
What are problems caused by chronic sleep deprivation?
increased risk of obesity, diabetes, cardio-vascular disease
What are problems with sleep medication?
produces grogginess and difficulty concentrating next day
What is sleep apnea?
Inability to sleep and breathe concurrently
What does sleep apnea do to blood?
Lack of breathing –> increased carbon dioxide in blood –> stimulates chemoreceptors [neurons that detect certain chemicals], and person wakes up gasping for air
What causes sleep apnea?
Low muscle tone in airways
Narrowness in airways
What is narcolepsy?
Periods of irresistible sleep, attacks of cataplexy, sleep paralysis and hypnagogic hallucinations
What is a narcoleptic sleep attack?
Overwhelming urge to sleep that can happen at any time
What happens in cataplexy?
Muscle weakness [sometimes completely paralysed] while fully conscious
What causes cataplexy?
muscle paralysis [part of REM sleep] happens at inappropriate time
What precipitates cataplexy?
Strong emotional reactions or physical effort - esp if caught unaware
Why do people with narcolepsy try to avoid strong emotions?
Can trigger cataplectic attacks
What is sleep paralysis?
Inability to move just before onset of sleep, or waking in the morning
How can person be brought out of sleep paralysis?
By being touched; called by name
What are hypnogogic hallucinations?
Dreaming while lying awake, paralysed [sleep paralysis + dreaming + awake]