Sleep Flashcards

1
Q

where do inhibitory processes associated with sleep arise?

A

Pons

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2
Q

where does evidence suggest that activity originates?

A

Reticular Formation

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3
Q

what part of the hypothalamus is involved in sleep inductions?

A

suprachiasmatic nuclei (SCN)

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4
Q

SCN activity?

A

stimulates the release of melatonin from the pineal gland

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5
Q

hypothalamus releases an excitatory neurotransmitter?

A

Orexin (hypocretin) which are required for wakefulness

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6
Q

four main types of patterns on EEG?

A

Alpha
Beta
Delta
Theta

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7
Q

EEG in relaxed awake state?

A

high frequency and high amplitude

a-waves

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8
Q

EEG in alert wake state?

A

high frequency and low amplitude

b-waves

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9
Q

Stage 1 sleep cycle?

A

slow wave, non-REM sleep

high amplitude and low frequency theta waves

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10
Q

Stage 2 sleep cycle?

A

no eye movement

bursts of rapid waves called sleep spindles

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11
Q

Stage 3 sleep cycle?

A

high amplitude and very slow delta waves

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12
Q

Stage 4 sleep cycle?

A

exclusively delta waves

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13
Q

what stages of sleep are ‘deep sleep?’

A

stages 3 & 4

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14
Q

what is of note as you go from awake to stage 4 sleep?

A

increasing amplitude and decreasing frequency

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15
Q

how often does REM sleep happen?

A

5-30 mins every 90 mins or so

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16
Q

what is REM sleep dependent on?

A

cholinergic pathways within the reticular formation and their projections to the thalamus, hypothalamus and cortex

17
Q

what increases time spent in REM?

A

anticholinesterases

18
Q

what is narcolepsy linked to?

A

dysfunction orexin release from the hypothalamus