sleep 1 Flashcards

1
Q

what stage of sleep eats up 50% of time sleeping

A

stage 2

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2
Q

what stages of sleep are considered deep sleep

A

stage 3 and 4

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3
Q

what neurotransmittors cause sleepiness

A

GABA
Melatonin
Adenosine

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4
Q

all patients with insomnia should have what 3 types of ‘treatment’

A
  1. identifying the cause
  2. patient education on sleep hygiene
  3. stress management
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5
Q

what type of insomnia is characterized by an acute stressor, and good sleep hygiene

A

transient insomnia

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6
Q

what type of insomnia can last up to 3 weeks, usually due to stress

A

short term insomnia

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7
Q

what is common denominator treatment of all 3 types of insomnia

A

educate on good sleep hygeine

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8
Q

what is an ideal agent for insomnia do?

A
  1. fast onset
  2. maintain sleep
  3. no hangover
  4. no tolerance
  5. no abuse potential
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9
Q

what are the 3 most common antihistamines used for sleep

A
  1. diphenhydramine
  2. doxylamine
  3. pyrliamine
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10
Q

what are 2 contraindications for antihistamines

A
  1. closed angle glaucoma

2. urinary obstruction

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11
Q

what antidepressants are most common for treating insomnia

A
  1. amitriptyline
  2. trazodone
  3. mirtazepine
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12
Q

what is the precursor to serotonin and melatonin

A

L-tryptophan

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13
Q

what are the 4 most commonly used drugs for treating insomnia

A
  1. traditional benzodiazepines
  2. zolpidem
  3. zaleplon
  4. eszopiclone
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14
Q

why should benzodiazepines be avoided for insomnia

A

increase time in stage 2; but decrease stage 3, 4, and 5 (deep sleep and REM)

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15
Q

what benzodiazepine has a very short half life and is often used for insomnia

A

triazolam

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16
Q

what adverse effect is seen with all nonbenzo GABA agonists

A

amnesia

17
Q

what drug works best for people needing help falling asleep but don’t have problems staying asleep

A

zaleplon (sonata)