schizo2 Flashcards
what are 3 characteristics of atypical antipsychotics
- lower risk of extrapyramidal symptoms
- risk of tardive dyskinesia is reduced
- can block 5HT2 receptors (helps w/ negative symptoms)
why is clozapine not first line for schizophrenia
CBC count needed every two weeks for 1 year
who is contraindicated for clozapine
WBC less than 3500
what are the BBW of clozapine
- agranulocytosis
- seizures
- dementia
- myocarditis
- othostatic hypotension
- respiratory arrest
what are adverse effects of risperidone
- hyperproactinemia
- sexual dysfunction
- sedation
- weight gain
risperidone is a good choice for what patients? why
elderly; not much anticholinergic activity
what is an important counselin point with paliperidone
take with food
what drug is the active metabolite of risperidone
paliperidone (invega)
what atypical is similar to olanzapine but not associated with agranulocytosis
olanzapine (zyprexa)
what is the agent of choice for a schizophrenic patient with Parkinson’s disease
quetiapine
what atypical antipsychotic is a partial D2 agonist
aripiprazole
what is the adverse effects of abilify
headache anxiety insomnia akathisia pathological gambling
what drug should be counseled to not swallow table; sublingual
asenapine
what drug has low risk of metabolic effects but high risk of orthostasis
iloperidone
what are the sedating atypicals
clozapine
olanzapine
quetiapine
asenapine
