depression 3 Flashcards
what ed with?
depression and hypertensive cisis
what are the adverse effects of MAO-I
- orthostatic hypotension
- weight gain
- sexual dysfunction
what class of antidepressants is considered last line
MAO-I’s
why are MAOI’s so rarely used
diet restriction; can’t eat foods with tyramine
what antidepressant can be abruptly discontinued and claims to few sexual side effects and no weight gain
vortioxetine (Brintellix)
what antidepressants can be beneficial for patients with CV diseases or elderly patients
SSRIs
what antidepressants are beneficial for obese patients, or patients with low motivation or apathy
SNRIs
what antidepressants are beneficial for patients with neuropathic pain or migraines
TCAs
what antidepressants are beneficial for patients who smoke or are obese
bupropion
when are neurovegetative symptoms relieved by antidperessants
1-2 weeks
when are response to cognitive symptoms relieved by antidepressnats
3-4 weeks
what is the time period goal for response or remission to antidepressant therapy
6-8 weeks
when is the continuation phase after response to antidepressant
4-9 months
what 3 symptoms must be present for diagnosis of serotonin syndrome
- mental status change
- tachycardia
- neuromuscular abnormalities
what are the symptoms of serotonin syndrome
Heavy sweating Agitation Diarrhea Tremor Overactive reflexes Mental status changes Uncoordinated movements Clunus muscle spasms High Fever Shivering Tachycardia
