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Medicine > SLE > Flashcards

SLE Flashcards

1
Q

Which of the following is NOT a characteristic of vasculitis?

  • Bleeding.
  • Ischemia.
  • Hyperglycemia.
  • Immune response.
A

C

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2
Q

The primary vasculitis is classified into

A

Small - medium - large vessels vasculitis

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3
Q

Large vessels vasculitis like?

A

Takayasu’s arteritis - GCA - Cogan’s syndrome.

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4
Q

Medium vessels vasculitis

A

PAN - Buerger’s disease - Kawasaki disease - Primary angitis of CNS

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5
Q

Behcet disease is considered as ?

  • Large vessel vasculitis.
  • Medium.
  • Small.
  • Variable.
A

Variable

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6
Q

Wegener’s granulomatosis is also called

A

Granulomatous cholangitis

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7
Q

Drug induced vasculitis is considered?

  • small vessels.
  • Medium vessels.
  • Large vessels.
A

Small vessels (ANCA positive)

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8
Q

Primarily affects the aorta and its major branches?

  • GCA.
  • Poly arteritis nedosa.
  • Takayasu arteritis.
  • Kawasaki’s disease.
A

C

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9
Q

Mostly involves the cranial branches of the aorta?

A

Giant cell arteritis

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10
Q

30 years old asian female presented to the ER with pain in her calfs started one week ago, associated with fever, night sweats and malaise. On examination, there was decreased pulsations at the brachial arteries and 15 mmHg difference in the systolic BP between the arms. There was also bruit over the subclavian arteries. What is the most likely diagnosis? And what is the next step?

  • GCA.
  • Takayasu arteritis.
  • Polyarteritis nodosa.
  • Wegener’s granulomatosis.
A

B. Next step is angiogram.

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11
Q

Which of the following treatments should be given for a patient with Takayasu arteritis?

  • Methotrexate.
  • Anti TNF.
  • Prednisone.
  • amoxycillin.
A

C

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12
Q

70 years old male presented to the ER with 2 weeks Hx of temporal pain and headache. ESR and CRP were elevated and biopsy showed necrotising arteritis of the temporal arteries, what is the most likely diagnosis?

A

GCA

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13
Q

Which radiological studies is the best to diagnose GCA?

  • US.
  • CT.
  • X ray.
  • MRI.
A

US (halo sign)

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14
Q

Takayasu arteritis is best diagnosed by?

  • CT angio.
  • X ray.
  • MRI.
  • US.
A

CT angio

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15
Q

The steroid therapy for a patient with temporal arteritis should be maintained for up to ?

  • 6 months.
  • 1 year.
  • 2 to 3 years.
  • 5 years.
A

2 to 3 years

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16
Q

What is a must if temporal arteritis is suspected?

A

Start prednisone (1mg/ Kg) for at least 4 weeks and order a temporal artery biopsy.

17
Q

40 to 50% of patients with temporal arteritis has a coexisting?

A

polymyalgia rheumatica

18
Q

Characterized by hip and shoulder muscle pain and morning stiffness in addition to synovitis. BUT, RF and ACP are negative.

A

Polymyalgia rheumatica

19
Q

Affects the small and medium sized muscular arteries

A

Polyarteritis nodosa

20
Q

Associated with HBV

A

PAN

21
Q

Has mesenteric involvement and testicular pain or tenderness

A

PAN

22
Q

PMN invasion of all layers of the blood vessels leading to reduced luminal diameter, ischemia, infarction and aneurysms.

A

PAN

23
Q

Elevated ESR and P- ANCA are evident

A

PAN

24
Q

Characterized by oral mucous membrane changes, erythema and edema of the extremities.

A

Kawasaki disease

25
Q

Characterized by asthma and eosinophilia + positive P- ANCA

A

Churg strauss syndrome

26
Q

Characterized by sinusitis, oral ulcers + chest infiltrates and high RFT (hematuria)

A

Granulomatosis with polyangiitis

27
Q

Positive C- ANCA is present in 90% of patients with?

  • PAN.
  • Kawasaki disease.
  • GCA.
  • Wegener granulomatosis (granulomatosis with polyangiitis)
A

D

28
Q

Sinus disease + pulmonary disease + glumorulonephritis =

A

Granulomatosis with polyangiitis (wegener)

29
Q

How can we distinguish between PAN and Wegener?

A

In PAN there is NO pulmonary involvement

Medicine (19 decks)

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