PUD / GERD Flashcards

1
Q

Parietal Cells receptors

A

Acetylcholine + Gastrin + Histamine

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2
Q

CLF and CRF have increased risk of PUD due to

A

Increased gastrin levels and decreased defense mechanisms

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3
Q

Acute ulcers seen in patients with severe burns

A

Curling’s ulcers

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4
Q

Has antibiotic effect against H. Pylori

A

Bismuth

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5
Q

The gold standard test for diagnosing GERD

A

Ambulatory esophageal pH monitoring

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6
Q

The optimal technique for determining the presence and severity of esophagitis

A

Endoscopy

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7
Q

The only reliable test for detecting Barrett’s esophagus

A

Endoscopy

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8
Q

Superficial + not extending to the muscularis

A

Erosion

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9
Q

Necrotic + involving the muscularis

A

Acute ulcer

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10
Q

Necrotic + through the deep layer

A

Chronic ulcer

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11
Q

PUD most commonly affect ……. part of the stomach.

A

The anterior and posterior antrum

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12
Q

More common in patients with blood group O

A

Duodenal ulcer

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13
Q

Associated with increased serum pepsinogen

A

Duodenal ulcer

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14
Q

Common in middle aged

A

D. Ulcers

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15
Q

Common in late aged

A

Gastric ulcer

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16
Q

Associated with blood group A

A

G. Ulcer

17
Q

Impaired antral motility is associated with

A

G. Ulcer

18
Q

Produce large amount of urease, breaking down the urea to alkaline ammonia and CO2.

A

H. Pylori

19
Q

Zollinger Ellison cancer is more common in

A

G. Ulcers

20
Q

The confirmatory test for PUD

A

Endoscopy

21
Q

Radiological modality used for PUD

A

Barium meal study

22
Q

Sucralfate is

A

A coating drug for PUD

23
Q

Forms a complex with mucus

A

Bismuth

24
Q

The only FDA approved prostaglandin analogue

A

Mesoprostol

25
Q

Inhibits BAO and MAO and causes blurred vision and urinary retention as side effects

A

Anticholinergics

26
Q

Cimetidine, Ranitidine … are

A

H2 antagonists

27
Q

Decreases gastric acid secretion by inhibition of H K ATPase proton pump

A

PPI (omeprazole - Esomeprazole …)

28
Q

Best combination of drugs for PUD

A

PPI + Amoxicillin + Clarithromycin

29
Q

< 5 mm erosion of one fold

A

Grade A

30
Q

> 5mm

A

Grade B

31
Q

Several folds + <75%

A

Grade C

32
Q

Several folds + >75%

A

Grade D

33
Q

The most prevalent LA grade of esophagitis

A

Grade B

34
Q

The optimal technique for detecting the presence and the severity of esophagitis

A

Endoscopy

35
Q

Inhibits transient LES relaxation post prandial

A

Baclofen

36
Q

Small flexible band used to treat GERD

A

Linx system