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Medicine > Brucellosis And Typhoid Fever > Flashcards

Brucellosis And Typhoid Fever Flashcards

1
Q

Brucella is gram?

A

Negative + intracelular

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2
Q

The animal reservoir:
Goats
Sheep
Camels

A

B. Melitensis

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3
Q

Cows , buffalo

A

B. Abortus

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4
Q

Pigs

A

B. Suis

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5
Q

Ingestion of raw milk and undercooked meat leads to?

A

Brucellosis

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6
Q

IP of brucella is?

A

5 days to 3 months

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7
Q

The commonest clinical manifestation of brucellosis is?

A

Undulant fever (intermittent + variable duration)

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8
Q

Which of the following is NOT a complication of brucellosis?

  • Arthritis.
  • Spondylitis.
  • Osteomyelitis.
  • Epididymo-orchitis.
  • Chronic fatigue.
  • Liver failure.
A

Liver failure

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9
Q

The most specific test of brucellosis?

A

Blood culture

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10
Q

Titres of non endemic areas of brucellosis?

A

> 1:160

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11
Q

Titres of endemic areas of brucellosis?

A

> 1:320

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12
Q

Typhoid fever is caused by?

A

Salmonella enterica

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13
Q

Transmitted by close contact or ingestion of contaminated food or water?

A

Typhoid fever

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14
Q

IP of salmonella enterica ?

A

5 to 21 days

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15
Q

Raising fever + chills + constipation occurs in which week of typhoid fever illness?

A

1st week

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16
Q

Abdominal pain and “rose spots” are seen in?

A

2nd week of typhoid fever

17
Q

excretion of the organism in stool or urine >12 months after acute infection.

A

Chronic salmonella carriage

18
Q

The most sensitive routinely available diagnostic tool of typhoid fever?

A

BM culture

19
Q

Chronic salmonella carriage should be treated with?

A

4 weeks of fluoroquinolone

20
Q

Doxycycline + rifampicin for 6 months are used to treat?

  • Brucellosis.
  • Typhoid fever.
  • TB.
  • HIV.
A

Brucellosis

21
Q

Used for preventing relapse of brucellosis?

  • Doxycycline 6w + streptomycin 2-3w.
  • Doxycycline 2-3w + streptomycin 6w.
22
Q

Which of the following can be used as a substitute for streptomycin in the Tx of brucellosis?

  • Primaquine.
  • Cephalosporins.
  • Gentamicin.
  • Vancomycin.
A

Gentamicin

23
Q

Pregnant women with brucellosis is treated with?

A

Rifampicin alone or with TMP-SMX

24
Q

Has three surface antigens O,H and Vi.

A

Salmonella

25
Q

Caused by salmonella paratyphi?

A

Para typhoid fever

26
Q

Used for detecting carriers of salmonella?

27
Q

Used to treat patients with suspected or known typhoid fever?

A

Dexamethasone

28
Q

Used for children above 2 y old to prevent typhoid fever?

A

Injectable polysaccharides (Vi-PS)

29
Q

Used for children above 5 y old to prevent typhoid fever?

A

Live attenuated oral Ty21a

Medicine (19 decks)

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