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PHRM 865 > Skin & Soft Tissue Infections (Erdman) > Flashcards

Skin & Soft Tissue Infections (Erdman) Flashcards

1
Q

What patient group is most likely to develop impetigo?

A

children

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2
Q

What is the predominant bacteria in impetigo?

A

mostly S. aureus and Streptococcus pyogenes (Group A)

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3
Q

True or false: non-bullous impetigo is highly contagious.

A

true

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4
Q

What topical therapies are best for MILD impetigo?

A

mupirocin 2% or retapamulin 1% ointment

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5
Q

What is the recommended duration of therapy for topical impetigo treatment?

A

5 days

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6
Q

What is the recommended duration of treatment for PO impetigo therapy?

A

7 days

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7
Q

What are the potential PO antibiotic therapies for adult impetigo?

A
  • dicloxacillin
  • cephalexin
  • erythromycin
  • clindamycin
  • Augmentin
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8
Q

What are the potential PO antibiotics for pediatric impetigo?

A
  • cephalexin
  • erythromycin
  • clindamycin
  • Augmentin
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9
Q

What organism is erysipelas caused by?

A

β-hemolytic streptococci

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10
Q

What condition is recognizable by peau d’orange?

A

erysipelas

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11
Q

What are the most prominent causative organisms in cellulitis?

A

S. aureus and S. pyogenes

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12
Q

When should CA-MRSA be suspected in a cellulitis patient?

A

if their infection includes an abscess or drainable focus of infection, or unresponsive to β-lactams

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13
Q

What organisms should empiric cellulitis therapy be directed against?

A

S. aureus and group A strep

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14
Q

What drug is best for Streptococcus pyogenes cellulitis?

A

penicillin

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15
Q

What drugs are best for MRSA cellulitis?

A
  • Bactrim
  • clindamycin (PO)
  • vancomycin (IV)
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16
Q

What drugs are best for Gram (-) cellulitis?

A
  • 3rd generation cephalosporins
  • extended-spectrum penicillins
  • fluoroquinolones
17
Q

What drugs are best for polymicrobial cellulitis?

A

Zosyn or carbapenems

18
Q

What is the minimum duration of therapy for cellulitis treatment?

A

5 days

19
Q

What are the recommended drugs for mild/moderate cellulitis with no MRSA suspected (adults and children)?

A
  • dicloxacillin
  • cephalexin
20
Q

What are the recommended drugs for mild/moderate cellulitis with MRSA suspected (adults and children)?

A
  • Bactrim
  • clindamycin
  • linezolid
21
Q

What are the recommended drugs for moderate-severe cellulitis with no MRSA suspected (adults and children)?

A
  • nafcillin
  • cefazolin
22
Q

What are the recommended drugs for moderate-severe cellulitis with MRSA suspected (adults and children)?

A
  • vancomycin
  • linezolid
23
Q

What organism is the main offender in necrotizing fasciitis?

A

S. pyogenes (same as cellulitis, but it’s toxin-producing)

24
Q

What is the primary treatment modality for necrotizing fasciitis?

A

surgery

25
Q

What is the recommended antibiotic regimen for necrotizing fasciitis?

A
  • vancomycin + Zosyn OR
  • meropenem + clindamycin
26
Q

True or false: all diabetic foot wounds are infected.

A

false

27
Q

What antibiotics would be appropriate for mild DFI?

A
  • cephalexin
  • dicloxacillin
  • Augmentin
28
Q

What antibiotics would be appropriate for mild DFI with suspected MRSA?

A
  • clindamycin
  • Bactrim
29
Q

What antibiotics would be appropriate for moderate DFA?

A
  • cefazolin IV (or vancomycin if MRSA risk factors)
  • ceftriaxone IV if suspected Enterobacteriaceae
    • Flagyl PO if suspected anaerobes
30
Q

What antibiotics would be appropriate for severe DFI?

A
  • vancomycin + Zosyn
  • meropenem
  • ceftazidime or cefepime with PO Flagyl
  • levofloxacin/ciprofloxacin + PO Flagyl
31
Q

What is the recommended duration of therapy for mild DFI?

A

1-2 weeks (up to 4)

32
Q

What is the recommended duration of treatment for moderate DFI?

A

1-3 weeks

33
Q

What is the recommended duration of treatment for severe DFI?

A

2-4 weeks

PHRM 865 (59 decks)

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