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Dermatology > Skin Reactions & Vesiculobullous Disorders > Flashcards

Skin Reactions & Vesiculobullous Disorders Flashcards

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Dermatology Board Prep flashcards
1
Q

wheals that are transient, irregular, edematous papules and plaque that are pruritic

A

urticaria

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2
Q

inducible form of urticaria that appears within 6-7 mins and resolves in 15-30 mins

A

dermatographism

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3
Q

what is urticaria with any other body system dysregulation due to an immune response considered?

A

anaphylaxis

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4
Q

a patient presents with pruritic sharply defined wheals that are raised, erythematous, irregular and annular. they become confluent across their arm. what is the diagnosis and 1st line treatment options (3)?

A

urticaria

2nd gen antihistamine:
loratadine
cetirizine
fexofenadine

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5
Q

a patient presents with this skin condition and the first line treatment is not working. what is the diagnosis and what are 3 adjust treatment options?

A

urticaria

steroids
montelukast
cyclosporine

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6
Q

skin reaction to UV radiation

A

photosensitivity reaction

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7
Q

skin changes mimicking normal sunburn changes

A

sunburn type photosensitivity reaction

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8
Q

macules, papules, or plaques similar to eczematous dermatitis

A

rash - photosensitivity reaction

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9
Q

sun exposure causes immune-mediated urticaria

A

urticarial photosensitivity reaction

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10
Q

a patient presents with pain on skin, fever, malaise, erythema, edema, vesicles/bullae and weeping/cracking skin. what is the diagnosis?

A

photosensitivity reaction

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11
Q

what is the treatment for photosensitivity reaction that presents with vesicular, weeping lesions?

A

cover + keep them clean
with cooling + soothing dressings

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12
Q

what is some education to give a patient with photosensitivity reaction? (2)

A

avoid UV light
wear sunscreen

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13
Q

what med can be used for photoallergic reactions?

A

steroids

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14
Q

what is acanthosis nigricans often associated with?

A

skin tags

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15
Q

what does rapid onset of acanthosis nigricans increase the risk of?

A

malignant etiology

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16
Q

acanthosis nigricans without associated endocrine disorder

A

type 1; hereditary bengin

17
Q

acanthosis nigricans + endocrine disorders associated with insulin resistance and diabetes

A

type 2; benign

18
Q

acanthosis nigricans associated with obesity, more common in patients with darker pigments and concurrent metabolic syndrome

A

type 3; pseudo-acanthosis nigricans

19
Q

acanthosis nigricans + use of nicotinic acid in high doses, and other medication

A

type 4; drug-induced

20
Q

acanthosis nigricans + adenocarcinoma of gastrointestinal or genitourinary tract

A

type 5; malignant

21
Q

a patient presents with darkening of skin pigmentation + velvety and skin lines accentuated. what is the diagnosis + treatment?

A

acanthosis nigricans

treat underlying disorder

22
Q

what is the first line diagnostic for acanthosis nigricans? what are the specific diagnostics?

A

rule out diabetes + prediabetes

fasting/random glucose + HgbA1c

23
Q

a bullous autoimmune disease usually seen in geriatric patients

A

bullous pemphigoid

24
Q

a patient presents with erythematous pruritic, papular/urticarial lesions with large tense bullae and erosive mucosal lesions. on exam, there is a negative nikolsky sign. what is the diagnosis and treatment (3)?

A

bullous pemphigoid

refer to derm - steroids, IV immunoglobulin, methotrexate

25
Q

a patient presents with this skin lesion. what is the diagnosis and 2 diagnostics that can be done?

A

bullous pemphigoid

biopsy linear IgG deposits
serum IgG antibodies

26
Q

an autoimmune disorder of the skin and mucous membranes due to loss of cell adhesion, leading to faccid bullae and weak surfaces that rupture.

A

pemphigus vulgaris

27
Q

a patient presents with painful and tender mouth lesions + epistaxis, hoarseness, and dysphagia. what is the diagnosis and treatment (2)?

A

pemphigus vulgaris

refer to derm - steroids + methotrexate

28
Q

a patient presents with erosions with blood and crust. on exam, there is a positive nikolsky sign. what is the diagnosis and treatment?

A

pemphigus vulgaris

refer to derm - steroids + methotrexate

29
Q

a patient presents with these lesions. what is the diagnosis? what are 2 diagnostics that can be done?

A

pemphigus vulgaris

biopsy
serum IgG antibodies

30
Q

a biopsy stained with direct immunofluorescence (IF) reveals IgG and compliment C3 deposited in lesional and paralesional skin within the intercellular substance of the dermis. what is the diagnosis?

A

pemphigus vulgaris

Dermatology (15 decks)

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