Skin (Integumentary System) Flashcards
What is the difference between thin and thick skin?
- thin: epidermis is 75-150 microns thick
- thick: epidermis is 400-600 microns thick
What are the 5 functions of skin?
- resistance to trauma and infection
- water retention
- vitamin D synthesis
- thermoregulation
- non-verbal communication
What are the 5 cells of the epidermis?
stem cells, keratinocytes, melanocytes, tactile/Merkel cells, dendritic/Langerhans cells
What are the 5 layers of the epidermis?
- stratum basale
- stratum spinosum
- stratum granulosum
- stratum lucidum (only thick skin)
- stratum corneum
- What are the characteristics of stratum basale?
- deepest layer, composed of a single row of cuboidal or columnar keratinocytes that contain scattered tonofilaments (intermediate filaments)
- stem cells undergo cell division to produce new keratinocytes
- melanocytes, Langerhans cells, and Merkel cells associated with tactile discs are scattered among the keratinocytes
- spinosum?
- 8-10 rows of many-sided keratinocytes with bundles of tonofilaments (intermediate filaments)
- includes projections of melaoncytes and Langerhans cells
- granulosum?
- 3-5 rows of flattened keratinocytes, in which organelles are beginning to degenerate
- cells contain the protein keratohyalin (converts tonofilaments into keratin) and lamellar granules (which release a lipid-rich, water-repellent secretion)
- lucidum?
- present only in skin of fingertips, palms, and soles
2. 3-5 rows of clear, flat, dead keratinocytes with large amounts of keratin
- corneum?
25-30 rows of dead, flat keratinocytes that contain mostly keratin
What are the characteristics of the dermis?
- cells: fibroblasts
- fibers: mostly collagen, some elastic, some reticular fibers
- dermal papillae, epidermal ridges
- 2 zones: papillary layer (relatively superficial) and reticular layer (deeper)
What are the characteristics of the papillary region of the dermis?
- superficial portion of the dermis (1/5)
- consists of (loose) areolar CT with elastic fibers
- contains dermal papillae that house capillaries, corpuscles of touch, and free nerve endings
What are the characteristics of the reticular region of the dermis?
- deeper portion of the dermis (4/5)
- consists of dense IRREGULAR CT with bundles of collagen and some coarse elastic fibers
- spaces between fibers contain some adipose cells, hair follicles, nerves, sebaceous glands, and sudoriferous glands
What are the characteristics of tension lines?
- collagen fibers
2. langer lines: wound healing consideration
The hypodermis/subcutaneous layer
- superficial fascial layer
2. subcutaneous fat
What happens during the inflammatory phase?
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