3.1 Epithelial Tissues Flashcards
What are the 4 primary tissue classes?
- epithelial tissue
- connective tissue
- nervous tissue
- muscular tissue
What are the 4 cell junctions of epithelial tissues?
- desmosomes
- hemidesmosomes
- tight junctions
- gap junctions
What are desmosomes?
they are found between cells (proteinaceous plaque and threads)
What are hemidesmosomes?
they anchor cells into the basement membrane
What are tight junctions?
they hold and pack cells together (like plastic wrap on a 6-pack of cans)
What are gap junctions?
- they are the only communicating cell connections
- they are especially rich in smooth and cardiac muscles
What are the 3 functions of epithelial tissues?
- protection (dermis)
- secretion (glands)
- absorption (microvilli)
What are the 3 different layers of epithelial tissues?
- simple/pseudostratified
- stratified
- transitional
What are the basic types/shapes of epithelial tissues?
- squamous (flat)
- cuboidal (nucleus is round and center of the cell)
- columnar (nucleus is elliptical and near base of the cell)
- transitional (transitions between squamous and cuboidal)
What does epithelial tissue look like?
- apical surface
- lateral surfaces
- basal surface
- basement membrane (basal lamina + reticular lamina + hemidesmosomes)
- connective tissue
How are tissues prepared?
- dehydrated and defatted, accomplished with changes of xylene and alcohol (“fixation”)
- embedded in paraffin blocks and sectioned into thin sections by histotechnologists
- slides commonly stianed with Hemotoxylin (purplish-blue) and Eosin (orange-pink)
- What are the 3 characteristics of simple squamous epithelium?
- flattened cells, squashed, “fried eggs”
- thin layers allow diffusion and osmosis
- locations: alveoli, lining of blood vessels (endothelium)
- What are the 2 characteristics of simple cuboidal epithelium?
- single layer of cube-shaped cells; nucleus is round and centered. Cells are arranged in a circle around the lumen
- locations that are ducts: glands - pancreas, thyroid, salivary glands
- What are the 4 characteristics of simple columnar epithelium?
- column-shaped cells; elliptical nuclei near the base.
- goblet cells make mucus (protection)
- microvilli extant on cells of the GI tract; none on goblet cells –> increased absorptive surface area
- no blood vessels in the epithelium layer
- locations that have microvilli and needed for absorption: stomach, small intestine, gallbladder
- What are the 4 characteristics of simple columnar CILIATED epithelium?
- ciliated column-shaped cells; elliptical nuclei near the base
- goblet cells make mucus (protection)
- cilia wave substances across surface (such as eggs in fallopian tubes)
- locations: fallopian tubes, ovaries (female reproductive tract)
- What are the 4 characteristics of pseudostratified CILIATED columnar epithelium?
- ciliated column-shaped cells; elliptical nuclei near the base. Looks stratified but each cell makes contact with the basement membrane
- goblet cells make mucus (protection)
- cilia wave substances across surface (from deep in lungs, out). If damaged, will be replaced with squamous keratinized - why?
- locations: trachea and bronchioles
- What are the 3 characteristics of transitional epithelium?
- transitions between simple & stratified arrangement, and between cuboidal/dome-shaped to squamous/flattened cells
- the ONLY epithelium that is binucleate; other binucleate epithelia would be considered malignant
- locations: lines urinary bladdar and ureters
- What are the 4 characteristics of stratified squamous non-keratinized epithelium?
- layered squamous cells
- diffusion and osmosis is difficult
- upper layers will slough off
- locations that can withstand desiccation: lines mouth, vaginal canal, cervix
- What are the characteristics of stratified cuboidal epithelium?
locations for a more robust lining: exocrine glands (salivary glands)