3.2 Connective Tissues Flashcards
What are the 8 functions of connective tissues?
- binding of organs
- support (cartilage)
- physical protection
- immune protection (loose areolar CT; macrophages, neutrophils, eosinophils, mast cells, plasma cells)
- movement (bone)
- storage (adipose CT)
- heat production (adipose CT)
- transport (oxygen, nutrients, blood is a connective tissue)
What are the 3 elements of connective tissues?
- ground substance (matrix) is where connective tissue sets: glycosaminoglycans (GAGs), proteoglycans, adhesive glycoproteins (sticky), hyaluronic acid
- cells: fibroblasts (make collagen fibers), macrophages/ neutrophils/eosinophils, mast cells (make histamines), plasma cells (make antibodies), adipocytes (fat cells for storage), chondrocytes (cartilage), osteocytes (bone)
- fibers: elastic fiber (in cartilage and muscles, NOT tendon), reticular fiber (Type II collagen, in LNs and BM), collagenous fiber
What are the 5 types of fibrous connective tissue?
- loose (areolar) CT
- dense CT (regular & irregular): both are made of collagen and fibers (have fibroblasts). Ex: dense regular CT in tendon, dense irregular CT in skin (messy, unorganized)
- (loose) areolar CT
- reticular CT
- adipose CT
What are the 4 characteristics of dense IRREGULAR CT?
- cells: fibroblasts
- fibers: collagen fibers in irregular masses
- locations: tough physical support (skin), other areas
- looks scattered and unorganized
What are the 4 characteristics of dense REGULAR CT?
- cells: fibroblasts
- fibers: collagen fibers in regular, parallel arrangement
- locations: robust capsules of organs (liver and spleen), source of tensile strength (ligaments and tendons), bands of menisci
- looks highly organized, increased tensile strength
- no blood vessels running through tendons and ligaments, so they don’t repair the same way. Ex: athletes walk slower
What are the 4 characteristics of (LOOSE) areolar CT?
- cells: fibroblasts, immune cells such as mast cells (histamine granules)
- fibers: collagen fibers (and elastic and reticular fibers)
- locations: skin, other areas
- functions: padding/packing
What are the 2 characteristics of reticular CT?
- cells: fibroblasts
- fibers: reticular fibers (Type II collagen, delicate, branched; hold lymphocytes together)
- locations: lymph nodes, liver, BM, other areas
- functions: architectural in function, provides construct/scaffolding for cellular components
What are the 4 characteristics of adipose CT?
- cells: adipocytes
- fibers: collagen fibers
- locations: anywhere
- functions: padding, energy storage. Can become mitotically active - tumor/lipoma develops where you get injured a lot
What are the 4 characteristics of cartilage (highly specialized CT)?
- chondroblasts (developing)
- lacunae (empty space/lake)
- chondrocytes (mature)
- perichondrium
What are the 3 types of cartilage?
- hyaline (weakest)
- elastic
- fibrocartilage (greatest tensile strength (spinal cord, temporal menipular joint)
What is perichondrium?
specialized membrane composed of fibroblasts (collagen). Only found in hyaline and elastic cartilage, not fibrocartilage
What are the 6 characteristics of hyaline cartilage?
- cells: chondrocytes
- fibers: NONE
- locations: ribs, tracheal rings, growth plate of bone
- hyaline oxidizes to become bone; all adults have a thin layer of hyaline in their joints that can be worn away
- fewer cells than matrix; chondrocytes are in lacunae, surrounded by capsule (protects the cells)
- surrounded by perichondrium since it is the weakest of cartilages
What are the 6 characteristics of elastic cartilage?
- cells: chondrocytes
- fibers: elastic fibers found in matrix/ground substance
- locations: ears, tip of nose
- tissue has great elasticity and memory for shape
- chondrocytes are in lacunae, surrounded by capsule
- surrounded by perichondrium
What are the 6 characteristics of fibrocartilage?
- cells: chondrocytes, fibroblasts?
- fibers: collagen fibers found in matrix/ground substance
- locations: intervertebral disks, menisci, and TMJ disk
- it is the strongest of cartilages; load-bearing, great tensile strength
- chondrocytes are in lacunae, surrounded by capsule
- NO perichondrium needed
What are the 2 types of bone (highly specialized CT)?
- cells: osteocytes
- fibers: collagen fibers
- types:
- spongy
- compact: contains Haversian canals, concentric lamellae, osteocytes, osteon, canaliculi, periosteum