Skin Disease in Pregnancy Flashcards
What physiological changes occur to the skin in pregnancy?
- Pre-existing conditions often worsen
- Acne flares in 3rd trimester
- Increased pigmentation common - linea nigra
- Spider naevi
- Broad pink linear striae
- Hand and nipple eczema common post-partum
- Psoriasis
What managements of skin conditions are contraindicated in pregnancy?
- Oral or topical erythromycin
- Retinoids
- Topical steroids
- Methotrexate
- Roaccutane
What is Pemphigoid gestationis?
Rare pruritic AI bullous disorder
When does pemphigoid gestationis present in pregnancy?
Late 2nd or 3rd trimester
What are the signs and symptoms of pemphigoid gestationis?
Lesions begin on abdomen 50% of time → widespread clustered blisters, sparing face can occur
What is the management of pemphigoid gestationis in pregnancy?
- Relive pruritis and stop new blister formation
- Potent topical steroids
- Oral prednisolone
What is Polymorphic Eruption of Pregnancy?
Self-limiting pruritic inflammatory disorder
When does polymorphic eruption of pregnancy occur?
3rd trimester or immediately Post-partum
What are the signs and symptoms of polymorphic eruption of pregnancy?
- Begins on lower abdomen, involving pregnancy striae - can extend to thigh, buttocks, legs, arms, sparing umbilicus and rarely involves face, hands, feet
- In 70% of cases, lesions become confluent and widespread, resemble erythroderma
What is the management of polymorphic eruption of pregnancy?
Symptomatic relief
What are the complications of polymorphic eruption of pregnancy?
- Preterm delivery
- SGA
- Recurrence
What is Prurigo of Pregnancy?
Pruritic disorder that affects 20% of normal pregnancies
- No effect on mother or baby
What tests must be done for suspect prurigo of pregnancy?
- LFTs to rule out OC
- Presents with pruritis
When does prurigo of pregnancy occur?
- Early 3rd trimester of pregnancy
- Resolves after delivery
What are the signs and symptoms of prurigo of pregnancy?
Present as excoriated papules on extensor limbs, abdomen, shoulder