Pregnancy Contraindicated Drugs

Question 1

What antibiotics are contraindicated in pregnancy?

Answer 1

• Sulphonamides - NTDs
• Chloramphenicol - Grey baby syndrome
• Ciprofloxacin
• Tetracycline
• Trimethoprim

Question 2

What psychiatric drugs are contraindicated in pregnancy?

Answer 2

• BDZ - cleft lip
• Lithium - Ebstein’s abnormality
• Sodium valporate - NTDs
• Carbamazepine - NTDs
• Paroxetine - malformations

Question 3

What miscellaneous drugs are contraindicated in pregnancy?

Answer 3

• ACEi
• Methotrexate
• NSAIDs
• Liraglutide
• Gliclazide
• Warfarin (in 1st and 3rd trimester)

Question 4

What antibiotics are contraindicated while breastfeeding?

Answer 4

• Sulphonamides - kernicterus
• Chloramphenicol - BM toxic
• Ciprofloxacin
• Tetracycline

Question 5

What psychiatric drugs are contraindicated while breastfeeding?

Answer 5

• BDZ
• Lithium
• Clozapine

Question 6

What miscellaneous drugs are contraindicated while breastfeeding?

Answer 6

• ACEi
• Sulphonylurea
• Aspirin
• Cytotoxic drugs
• Carbimazole
• Fluconazole
• Amiodarone

Question 7

Which anti-epileptics are recommended in pregnancy?

Answer 7

• Lamotrigine and carbamazepine
  
  • Use lowest dose possible if it must be used at all

Question 8

What are the signs of foetal hydantoin syndrome?

Answer 8

• IUGR
• Microcephaly
• Cleft lip/palate
• Mental retardation
• Hypoplastic fingernails
• Distal limb deformities

Question 9

What medications are known to cause foetal hydantoin syndrome?

Answer 9

• Phenytoin
• Carbamazepine