Physiological Changes in Pregnancy Flashcards

1
Q

How does energy demands change in pregnancy?

A

14% increased demand:

  • Increased fat storage (4kg stored)
  • Less protein requirement
  • Insulin sensitivity decreases
    • Mother absorbs less glucose
    • More glucose available for baby
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2
Q

How does the anatomy change in pregnancy?

A
  • Striae gravidarum (abdomen)
  • Stria distensae (medial thigh)
  • Linea nigra
  • Chloasma gravidarum (mask of pregnancy)
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3
Q

What cardiac changes occur in pregnancy?

A
  • CO increased 50%
  • SV increased 35%
  • Less peripheral resistance - progesterone
  • HR increased 15-25%
  • LAD on CXR due to compensatory LVH
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4
Q

What respiratory changes occur in pregnancy?

A
  • Tidal volume increased 30-50%
    • Increased minute ventilation
    • Feeling of breathlessness
  • FRC decreases
  • RR does not change
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5
Q

What renal changes occur in pregnancy?

A
  • More aldosterone created = fluid retention
  • GFR increases in 1st trimester
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6
Q

What haematological changes occur in pregnancy?

A
  • Macrocytosis
  • Neutrophilia
  • Thrombocytopenia
  • Dilutional anaemia
  • Increased VWF, F7, F8, fibrinogen, PAI-1/2
  • Decreased protein S
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7
Q

What endocrinological changes occur in pregnancy?

A
  • Biggest increase = oestriol
  • Less increase = oestrone, oestradiol
  • LH and FSH supressed
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