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MBChB221 Musculoskeletal > Skin > Flashcards

Skin Flashcards

1
Q

Layers of Epidermis

A

Stratum Corneum, Stratum Granulosum, Stratum Spinosum, Stratum Basale

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2
Q

Stratum Corneum

A

Dead Keratinocytes

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3
Q

Stratum Granulosum

A

Granular Keratinocutes

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4
Q

Stratum SPinosum

A

Keratinocytes anchored together by hemidesmosomes

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5
Q

Stratum Basale

A

Keratinocytes on the basement membrane

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6
Q

Two Epidermal Cell Types

A

Keratinocytes (90%), Melanocytes (10%)

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7
Q

Collagen Types

A

VII and III

VII = Linking BM to dermis
III = STandard dermis

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8
Q

Eumelanin

A

Brown / black

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9
Q

Phaeomelanin

A

Yellow / red

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10
Q

Vitiligo

A

Autoimmune disease in embryo that destroys melanocytes

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11
Q

Keratin Types Epidermis

A

1 and 2

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12
Q

Dermis Contents

A

Mucopolysaccharides, elastin and collagen, blood vessels, fibroblasts, immune cells

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13
Q

Cuticle

A

Dead skin directly superficial to eponychium

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14
Q

Eponychium

A

Live skin at base of nail

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15
Q

Lunula

A

Superficial Growing area of nail

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16
Q

Matrix

A

Deep growing area of nail

17
Q

Nail Dystropy

A

Damage to matrix = can’t grow new nail

18
Q

Nail Bed

A

Deep nail

19
Q

Nail plate

A

Superficial nail

20
Q

Nail FOld

A

Border of nail

21
Q

Hyponychium

A

Live skin at free/far end of nail

22
Q

Hair Bulge Area

A

STEM Cells

23
Q

Hair Bulb

A

Root

24
Q

Pilocebaceous Gland

A

Sweat gland near hair

25
Q

Eccrine Sweat Gland Neurotransmitter

A

ACh

26
Q

Eccrine Sweat Gland Role

A

Cooling

27
Q

Hyperhidrosis

A

Excess Sweating

28
Q

Hyperhidrosis Treatment

A
  1. Block ACh (blocks everywhere = bad)
  2. Cut symp nerve supply to effected area
29
Q

Skin Immune Cells

A

Langherans cells, dermal dentritic cells

MBChB221 Musculoskeletal (26 decks)

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