Skin Flashcards
Layers of Epidermis
Stratum Corneum, Stratum Granulosum, Stratum Spinosum, Stratum Basale
Stratum Corneum
Dead Keratinocytes
Stratum Granulosum
Granular Keratinocutes
Stratum SPinosum
Keratinocytes anchored together by hemidesmosomes
Stratum Basale
Keratinocytes on the basement membrane
Two Epidermal Cell Types
Keratinocytes (90%), Melanocytes (10%)
Collagen Types
VII and III
VII = Linking BM to dermis
III = STandard dermis
Eumelanin
Brown / black
Phaeomelanin
Yellow / red
Vitiligo
Autoimmune disease in embryo that destroys melanocytes
Keratin Types Epidermis
1 and 2
Dermis Contents
Mucopolysaccharides, elastin and collagen, blood vessels, fibroblasts, immune cells
Cuticle
Dead skin directly superficial to eponychium
Eponychium
Live skin at base of nail
Lunula
Superficial Growing area of nail
Matrix
Deep growing area of nail
Nail Dystropy
Damage to matrix = can’t grow new nail
Nail Bed
Deep nail
Nail plate
Superficial nail
Nail FOld
Border of nail
Hyponychium
Live skin at free/far end of nail
Hair Bulge Area
STEM Cells
Hair Bulb
Root
Pilocebaceous Gland
Sweat gland near hair
Eccrine Sweat Gland Neurotransmitter
ACh
Eccrine Sweat Gland Role
Cooling
Hyperhidrosis
Excess Sweating
Hyperhidrosis Treatment
- Block ACh (blocks everywhere = bad)
- Cut symp nerve supply to effected area
Skin Immune Cells
Langherans cells, dermal dentritic cells
