skeletal tumours Flashcards

1
Q

osteochondromas are most common in

A

< 20

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2
Q

what is an osteochondroma

A
  • most common benign tumour
  • tumour of chondrocytes
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3
Q

most common areas affected by osteochondroma

A
  • knee
  • proximal femur
  • proximal humerus
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4
Q

osteochondroma diagnosis

A

radiology (seen as bony spur growing off the bone)

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5
Q

osteochondroma management

A

surgery

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6
Q

osteoid osteomas are most common in

A

boys < 20

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7
Q

what is an osteoid osteoma

A

tumour of osteoblasts

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8
Q

osteoid osteoma presentation

A

intense pain that is worse at night and relieved by NSAIDs

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9
Q

osteoid osteoma diagnosis

A

CT (metaphysis of long bones, lesions usually central)

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10
Q

osteoid osteoma management

A

resolve over time or with surgery

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11
Q

giant cell tumours are most common in

A

women 25-40

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12
Q

giant cell tumour diagnosis

A

radiology (soap bubble appearance at epiphysis or metaphysis of long bones, especially knee and wrist)

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13
Q

giant cell tumour management

A

curettage or resection

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14
Q

osteosarcomas are most common in

A

men < 25

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15
Q

what tumour can develop secondary to Paget’s in older patients

A

osteosarcoma

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16
Q

what are osteosarcomas

A
  • most common bone tumour
  • tumour of osteoblasts
17
Q

osteosarcoma diagnosis

A

radiology (sunray appearance of metaphysis of long bones, especially around knee)

18
Q

osteosarcoma management

A
  • combination of chemotherapy and surgery
  • resistant to radiotherapy
19
Q

chondrosarcomas are most common in

A

middle aged patients

20
Q

what are chondrosarcomas

A

tumours of chondrocytes

21
Q

chondrosarcoma: diagnosis

A

radiology (popcorn calcification at axial skeleton, especially around proximal femur or pelvis)

22
Q

chondrosarcoma management

A

surgery

23
Q

Ewing’s sarcomas are most common in

A

adolescent men

24
Q

what are Ewing’s sarcomas

A

primitive round cell neuro-ectodermal tumour

25
Q

Ewing’s sarcoma presentation

A

warm swelling and associated raised inflammatory markers

26
Q

Ewing’s sarcoma diagnosis

A

radiology (onion ring sign)

27
Q

Ewing’s sarcoma management

A

combination of chemotherapy, radiotherapy and surgery

28
Q

most common locations for bone metastasis

A
  • prostate
  • breast
  • small cell lung
  • kidney
  • thyroid
29
Q

what is Mirel’s score

A

scoring system used to identify patients with malignant bone tumours that are at high risk of fracture and would therefore benefit from prophylactic internal fixation

30
Q

factors used in Mirel’s score

A
  • site
  • location
  • size
  • lytic/sclerotic
31
Q

what does Mirel’s score > 8 suggest

A

benefit from internal fixation